Search Results

Overview

Uniprot IDQ70Z53
Protein NameProtein FRA10AC1
Gene NameFRA10AC1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
201 GYIEHGEKRNALVKL
260 AEEASKKKDKGHSSS
40 LLQKPFQKEKHGKVA
42 QKPFQKEKHGKVAHK
49 KHGKVAHKQVAAELL

Function

May be involved in pre-mRNA splicing

Protein Sequence

10 MHGHGGYDSD 20 FSDDERCGES 30 SKRKKRTVED 40 DLLLQKPFQK 50 EKHGKVAHKQ 60 VAAELLDREE 70 ARNRRFHLIA 80 MDAYQRHTKF 90 VNDYILYYGG 100 KKEDFKRLGE 110 NDKTDLDVIR 120 ENHRFLWNEE 130 DEMDMTWEKR 140 LAKKYYDKLF 150 KEYCIADLSK 160 YKENKFGFRW 170 RVEKEVISGK 180 GQFFCGNKYC 190 DKKEGLKSWE 200 VNFGYIEHGE 210 KRNALVKLRL 220 CQECSIKLNF 230 HHRRKEIKSK 240 KRKDKTKKDC 250 EESSHKKSRL 260 SSAEEASKKK 270 DKGHSSSKKS 280 EDSLLRNSDE 290 EESASESELW 300 KGPLPETDEK 310 SQEEEFDEYF QDLFL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Molecular Function GO:0016791 phosphatase activity
Biological Process GO:0000398 mRNA splicing, via spliceosome

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.