Search Results
Overview
| Uniprot ID | Q710C4 |
|---|---|
| Protein Name | Adenosylhomocysteinase |
| Gene Name | AHCY |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 186 | NVNDSVTKSKFDNLY |
| 188 | NDSVTKSKFDNLYGC |
| 204 | ESLIDGIKRATDVMI |
| 322 | AVEKVNIKPQVDRYL |
| 388 | VGVHFLPKKLDEAVA |
| 389 | GVHFLPKKLDEAVAE |
| 401 | VAEAHLGKLNVKLTK |
| 405 | HLGKLNVKLTKLTEK |
| 408 | KLNVKLTKLTEKQAQ |
Function
Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (By similarity). Binds copper ions (By similarity)
Protein Sequence
10
MSEKLPYKVA
20
DISLAAWGRK
30
ALDLAENEMP
40
GLMRMREMYS
50
ASKPLKGARI
60
AGCLHMTVET
70
AVLIETLVAL
80
GAEVRWSSCN
90
IFSTQDHAAA
100
AIAKAGIPVY
110
AWKGETDEEY
120
LWCIEQTLYF
130
KDGPLNMILD
140
DGGDLTNLVH
150
TKYPELLSGI
160
RGISEETTTG
170
VHNLYKMKAN
180
GILKVPAINV
190
NDSVTKSKFD
200
NLYGCRESLI
210
DGIKRATDVM
220
IAGKVAVVAG
230
YGDVGKGCAQ
240
ALRGFGARVI
250
ITEIDPINAL
260
QAAMEGYEVT
270
TMDEACQEGN
280
IFVTTTGCID
290
IILGRHFEQM
300
KDDAIVCNIG
310
HFDVEIDVKW
320
LNENAVEKVN
330
IKPQVDRYLL
340
KNGHRIILLA
350
EGRLVNLGCA
360
MGHPSFVMSN
370
SFTNQVLAQI
380
ELWTHPDKYP
390
VGVHFLPKKL
400
DEAVAEAHLG
410
KLNVKLTKLT
420
EKQAQYLGMS
430
REGPFKPDHY
RY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004013 | adenosylhomocysteinase activity |
| Molecular Function | GO:0051287 | NAD binding |
| Biological Process | GO:0006730 | one-carbon metabolic process |
| Biological Process | GO:0033353 | S-adenosylmethionine cycle |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.