Search Results
Overview
| Uniprot ID | Q71RC2 |
|---|---|
| Protein Name | La-related protein 4 |
| Gene Name | LARP4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 616 | VALQEPRKLSYAEVC |
Function
RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Essential for proper regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744)
Protein Sequence
10
MLLFVEQVAS
20
KGTGLNPNAK
30
VWQEIAPGNT
40
DATPVTHGTE
50
SSWHEIAATS
60
GAHPEGNAEL
70
SEDICKEYEV
80
MYSSSCETTR
90
NTTGIEESTD
100
GMILGPEDLS
110
YQIYDVSGES
120
NSAVSTEDLK
130
ECLKKQLEFC
140
FSRENLSKDL
150
YLISQMDSDQ
160
FIPIWTVANM
170
EEIKKLTTDP
180
DLILEVLRSS
190
PMVQVDEKGE
200
KVRPSHKRCI
210
VILREIPETT
220
PIEEVKGLFK
230
SENCPKVISC
240
EFAHNSNWYI
250
TFQSDTDAQQ
260
AFKYLREEVK
270
TFQGKPIMAR
280
IKAINTFFAK
290
NGYRLMDSSI
300
YSHPIQTQAQ
310
YASPVFMQPV
320
YNPHQQYSVY
330
SIVPQSWSPN
340
PTPYFETPLA
350
PFPNGSFVNG
360
FNSPGSYKTN
370
AAAMNMGRPF
380
QKNRVKPQFR
390
SSGGSEHSTE
400
GSVSLGDGQL
410
NRYSSRNFPA
420
ERHNPTVTGH
430
QEQTYLQKET
440
STLQVEQNGD
450
YGRGRRTLFR
460
GRRRREDDRI
470
SRPHPSTAES
480
KAPTPKFDLL
490
ASNFPPLPGS
500
SSRMPGELVL
510
ENRMSDVVKG
520
VYKEKDNEEL
530
TISCPVPADE
540
QTECTSAQQL
550
NMSTSSPCAA
560
ELTALSTTQQ
570
EKDLIEDSSV
580
QKDGLNQTTI
590
PVSPPSTTKP
600
SRASTASPCN
610
NNINAATAVA
620
LQEPRKLSYA
630
EVCQKPPKEP
640
SSVLVQPLRE
650
LRSNVVSPTK
660
NEDNGAPENS
670
VEKPHEKPEA
680
RASKDYSGFR
690
GNIIPRGAAG
700
KIREQRRQFS
710
HRAIPQGVTR
720
RNGKEQYVPP
RSPK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0010494 | cytoplasmic stress granule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0003730 | mRNA 3'-UTR binding |
| Molecular Function | GO:0008143 | poly(A) binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0045727 | positive regulation of translation |
| Biological Process | GO:0010608 | post-transcriptional regulation of gene expression |
| Biological Process | GO:0006412 | translation |
Reference
PMID: N/A