Search Results
Overview
| Uniprot ID | Q71RH2 |
|---|---|
| Protein Name | Ceramide synthase |
| Gene Name | TLCD3B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 182 | GKILIQYKQQHTLLH |
Function
Involved in ceramide synthesis
Protein Sequence
10
MLTPMVAGGV
20
VFPGLFLLSK
30
NTLQRLPQLR
40
WEEADAVIVS
50
ARLVSSVQAI
60
MASTAGYIVS
70
TSCKHIIDDQ
80
HWLSSAYTQF
90
AVPYFIYDIY
100
AMFLCHWHKH
110
QVKGHGGDDG
120
AARAPGSTWA
130
IARGYLHKEF
140
LMVLHHAAMV
150
LVCFPLSVVW
160
RQGKGDFFLG
170
CMLMAEVSTP
180
FVCLGKILIQ
190
YKQQHTLLHK
200
VNGALMLLSF
210
LCCRVLLFPY
220
LYWAYGRHAG
230
LPLLAVPLAI
240
PAHVNLGAAL
250
LLAPQLYWFF
260
LICRGACRLF
270
WPRSRPPPAC
QAQD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0000139 | Golgi membrane |
| Molecular Function | GO:0050291 | sphingosine N-acyltransferase activity |
| Biological Process | GO:0046513 | ceramide biosynthetic process |
| Biological Process | GO:0055088 | lipid homeostasis |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.