Search Results
Overview
| Uniprot ID | Q7L0J3 |
|---|---|
| Protein Name | Synaptic vesicle glycoprotein 2A |
| Gene Name | SV2A |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 515 | GGQYFNDKFIGLRLK |
Function
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)
Protein Sequence
10
MEEGFRDRAA
20
FIRGAKDIAK
30
EVKKHAAKKV
40
VKGLDRVQDE
50
YSRRSYSRFE
60
EEDDDDDFPA
70
PSDGYYRGEG
80
TQDEEEGGAS
90
SDATEGHDED
100
DEIYEGEYQG
110
IPRAESGGKG
120
ERMADGAPLA
130
GVRGGLSDGE
140
GPPGGRGEAQ
150
RRKEREELAQ
160
QYEAILRECG
170
HGRFQWTLYF
180
VLGLALMADG
190
VEVFVVGFVL
200
PSAEKDMCLS
210
DSNKGMLGLI
220
VYLGMMVGAF
230
LWGGLADRLG
240
RRQCLLISLS
250
VNSVFAFFSS
260
FVQGYGTFLF
270
CRLLSGVGIG
280
GSIPIVFSYF
290
SEFLAQEKRG
300
EHLSWLCMFW
310
MIGGVYAAAM
320
AWAIIPHYGW
330
SFQMGSAYQF
340
HSWRVFVLVC
350
AFPSVFAIGA
360
LTTQPESPRF
370
FLENGKHDEA
380
WMVLKQVHDT
390
NMRAKGHPER
400
VFSVTHIKTI
410
HQEDELIEIQ
420
SDTGTWYQRW
430
GVRALSLGGQ
440
VWGNFLSCFG
450
PEYRRITLMM
460
MGVWFTMSFS
470
YYGLTVWFPD
480
MIRHLQAVDY
490
ASRTKVFPGE
500
RVEHVTFNFT
510
LENQIHRGGQ
520
YFNDKFIGLR
530
LKSVSFEDSL
540
FEECYFEDVT
550
SSNTFFRNCT
560
FINTVFYNTD
570
LFEYKFVNSR
580
LINSTFLHNK
590
EGCPLDVTGT
600
GEGAYMVYFV
610
SFLGTLAVLP
620
GNIVSALLMD
630
KIGRLRMLAG
640
SSVMSCVSCF
650
FLSFGNSESA
660
MIALLCLFGG
670
VSIASWNALD
680
VLTVELYPSD
690
KRTTAFGFLN
700
ALCKLAAVLG
710
ISIFTSFVGI
720
TKAAPILFAS
730
AALALGSSLA
740
LKLPETRGQV
LQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0048786 | presynaptic active zone |
| Cellular Component | GO:0005911 | cell-cell junction |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0098982 | GABA-ergic synapse |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0031594 | neuromuscular junction |
| Cellular Component | GO:0043005 | neuron projection |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Cellular Component | GO:0030672 | synaptic vesicle membrane |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0022857 | transmembrane transporter activity |
| Biological Process | GO:0016082 | synaptic vesicle priming |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.