Search Results
Overview
| Uniprot ID | Q7Z3D6 |
|---|---|
| Protein Name | D-glutamate cyclase, mitochondrial |
| Gene Name | DGLUCY |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 385 | RAWNLHQKIVEDAVE |
Function
D-glutamate cyclase that converts D-glutamate to 5-oxo-D-proline
Protein Sequence
10
MPFTLHLRSR
20
LPSAIRSLIL
30
QKKPNIRNTS
40
SMAGELRPAS
50
LVVLPRSLAP
60
AFERFCQVNT
70
GPLPLLGQSE
80
PEKWMLPPQG
90
AISETRMGHP
100
QFWKYEFGAC
110
TGSLASLEQY
120
SEQLKDMVAF
130
FLGCSFSLEE
140
ALEKAGLPRR
150
DPAGHSQTTV
160
PCVTHAGFCC
170
PLVVTMRPIP
180
KDKLEGLVRA
190
CCSLGGEQGQ
200
PVHMGDPELL
210
GIKELSKPAY
220
GDAMVCPPGE
230
VPVFWPSPLT
240
SLGAVSSCET
250
PLAFASIPGC
260
TVMTDLKDAK
270
APPGCLTPER
280
IPEVHHISQD
290
PLHYSIASVS
300
ASQKIRELES
310
MIGIDPGNRG
320
IGHLLCKDEL
330
LKASLSLSHA
340
RSVLITTGFP
350
THFNHEPPEE
360
TDGPPGAVAL
370
VAFLQALEKE
380
VAIIVDQRAW
390
NLHQKIVEDA
400
VEQGVLKTQI
410
PILTYQGGSV
420
EAAQAFLCKN
430
GDPQTPRFDH
440
LVAIERAGRA
450
ADGNYYNARK
460
MNIKHLVDPI
470
DDLFLAAKKI
480
PGISSTGVGD
490
GGNELGMGKV
500
KEAVRRHIRH
510
GDVIACDVEA
520
DFAVIAGVSN
530
WGGYALACAL
540
YILYSCAVHS
550
QYLRKAVGPS
560
RAPGDQAWTQ
570
ALPSVIKEEK
580
MLGILVQHKV
590
RSGVSGIVGM
600
EVDGLPFHNT
610
HAEMIQKLVD
VTTAQV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0047820 | D-glutamate cyclase activity |
| Biological Process | GO:0006536 | glutamate metabolic process |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.