Search Results

Overview

Uniprot IDQ7Z3I7
Protein NameZinc finger protein 572
Gene NameZNF572
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
382 CRIQLGEKPYRCCEC

Function

May be involved in transcriptional regulation

Protein Sequence

10 MEQEKKLLVS 20 DSNSFMERES 30 LKSPFTGDTS 40 MNNLETVHHN 50 NSKADKLKEK 60 PSEWSKRHRP 70 QHYKHEDAKE 80 MPLTWVQDEI 90 WCHDSYESDG 100 KSENWGNFIA 110 KEEEKPNHQE 120 WDSGEHTNAC 130 VQQNSSFVDR 140 PYKCSECWKS 150 FSNSSHLRTH 160 QRTHSGEKPY 170 KCSECAKCFC 180 NSSHLIQHLR 190 MHTGEKPYQC 200 GECGKSFSNT 210 SHLIIHERTH 220 TGEKPYKCPE 230 CGKRFSSSSH 240 LIQHHRSHTG 250 EKPYECSVCG 260 KGFSHSYVLI 270 EHQRTHTGEK 280 PYKCPDCGKS 290 FSQSSSLIRH 300 QRTHTGEKPY 310 KCLECEKSFG 320 CNSTLIKHQR 330 IHTGEKPYQC 340 PECGKNFSRS 350 SNLITHQKMH 360 TGEKSYESSE 370 YEESLGQNCN 380 VIEECRIQLG 390 EKPYRCCECG 400 KSFGLSSHLI 410 RHQRTHTGEK 420 PYRCSECWKT 430 FSQSSTLVIH 440 QRTHTGEKPY 450 KCPDCGESFS 460 QSFNLIRHRR 470 THIGEKPYKC 480 TSCEKCFSRS 490 AYLSQHRKIH 500 VEKPFESPDV 510 GDFPHEWTWK 520 NCSGEMPFIS SFSVSNSSS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0001817 regulation of cytokine production
Biological Process GO:0002682 regulation of immune system process

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.