Search Results
Overview
| Uniprot ID | Q7Z3K6 |
|---|---|
| Protein Name | Mesoderm induction early response protein 3 |
| Gene Name | MIER3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 262 | LKCNHNIKEAIERYC |
| 483 | ERPAKRLKMGIAVPE |
Function
Transcriptional repressor
Protein Sequence
10
MAEASFGSSS
20
PVGSLSSEDH
30
DFDPTAEMLV
40
HDYDDERTLE
50
EEEMMDEGKN
60
FSSEIEDLEK
70
EGTMPLEDLL
80
AFYGYEPTIP
90
AVANSSANSS
100
PSELADELPD
110
MTLDKEEIAK
120
DLLSGDDEET
130
QSSADDLTPS
140
VTSHETSDFF
150
PRPLRSNTAC
160
DGDKESEVED
170
VETDSGNSPE
180
DLRKEIMIGL
190
QYQAEIPPYL
200
GEYDGNEKVY
210
ENEDQLLWCP
220
DVVLESKVKE
230
YLVETSLRTG
240
SEKIMDRISA
250
GTHTRDNEQA
260
LYELLKCNHN
270
IKEAIERYCC
280
NGKASQEGMT
290
AWTEEECRSF
300
EHALMLFGKD
310
FHLIQKNKVR
320
TRTVAECVAF
330
YYMWKKSERY
340
DYFAQQTRFG
350
KKRYNHHPGV
360
TDYMDRLVDE
370
TEALGGTVNA
380
SALTSNRPEP
390
IPDQQLNILN
400
SFTASDLTAL
410
TNSVATVCDP
420
TDVNCLDDSF
430
PPLGNTPRGQ
440
VNHVPVVTEE
450
LLTLPSNGES
460
DCFNLFETGF
470
YHSELNPMNM
480
CSEESERPAK
490
RLKMGIAVPE
500
SFMNEVSVNN
510
LGVDFENHTH
520
HITSAKMAVS
530
VADFGSLSAN
540
ETNGFISAHA
550
LHQHAALHSE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0042826 | histone deacetylase binding |
| Molecular Function | GO:0003714 | transcription corepressor activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.