Search Results

Overview

Uniprot IDQ7Z417
Protein NameFMR1-interacting protein NUFIP2
Gene NameNUFIP2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
146 VKANTFGKAGIKTKN
152 GKAGIKTKNFIQKNS
281 DGSKPIWKYETGPGG

Function

Binds RNA

Protein Sequence

10 MEEKPGQPQP 20 QHHHSHHHPH 30 HHPQQQQQQP 40 HHHHHYYFYN 50 HSHNHHHHHH 60 HQQPHQYLQH 70 GAEGSPKAQP 80 KPLKHEQKHT 90 LQQHQETPKK 100 KTGYGELNGN 110 AGEREISLKN 120 LSSDEATNPI 130 SRVLNGNQQV 140 VDTSLKQTVK 150 ANTFGKAGIK 160 TKNFIQKNSM 170 DKKNGKSYEN 180 KSGENQSVDK 190 SDTIPIPNGV 200 VTNNSGYITN 210 GYMGKGADND 220 GSGSESGYTT 230 PKKRKARRNS 240 AKGCENLNIV 250 QDKIMQQETS 260 VPTLKQGLET 270 FKPDYSEQKG 280 NRVDGSKPIW 290 KYETGPGGTS 300 RGKPAVGDML 310 RKSSDSKPGV 320 SSKKFDDRPK 330 GKHASAVASK 340 EDSWTLFKPP 350 PVFPVDNSSA 360 KIVPKISYAS 370 KVKENLNKTI 380 QNSSVSPTSS 390 SSSSSSTGET 400 QTQSSSRLSQ 410 VPMSALKSVT 420 SANFSNGPVL 430 AGTDGNVYPP 440 GGQPLLTTAA 450 NTLTPISSGT 460 DSVLQDMSLT 470 SAAVEQIKTS 480 LFIYPSNMQT 490 MLLSTAQVDL 500 PSQTDQQNLG 510 DIFQNQWGLS 520 FINEPSAGPE 530 TVTGKSSEHK 540 VMEVTFQGEY 550 PATLVSQGAE 560 IIPSGTEHPV 570 FPKAYELEKR 580 TSPQVLGSIL 590 KSGTTSESGA 600 LSLEPSHIGD 610 LQKADTSSQG 620 ALVFLSKDYE 630 IESQNPLASP 640 TNTLLGSAKE 650 QRYQRGLERN 660 DSWGSFDLRA 670 AIVYHTKEME 680 SIWNLQKQDP 690 KRIITYNEAM DSPDQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0010494 cytoplasmic stress granule
Cellular Component GO:0005829 cytosol
Cellular Component GO:0016020 membrane
Cellular Component GO:0016604 nuclear body
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005840 ribosome
Molecular Function GO:0003723 RNA binding

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[3] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.

[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.