Search Results
Overview
| Uniprot ID | Q863Z0 |
|---|---|
| Protein Name | Proteasome activator complex subunit 2 |
| Gene Name | PSME2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 15 | RLSGEARKQVDVFRQ |
| 154 | LERVNAVKTKVEAFQ |
| 156 | RVNAVKTKVEAFQTT |
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity)
Protein Sequence
10
MAKPCGVRLS
20
GEARKQVDVF
30
RQNLFQEAEE
40
FLYRFLPQKI
50
IYLSQLLQED
60
SLNVTDLTSL
70
RAPLDIPIPD
80
PPPKDDEMET
90
DKQEKKEVPK
100
CGFLPGNEKI
110
LALLGLVKPE
120
VWTLKEKCIL
130
VITWIQHLIP
140
KIEDGNDFGV
150
AVQEKVLERV
160
NAVKTKVEAF
170
QTTISKYFSE
180
RGDAVAKASK
190
ETHVMDYRAL
200
VHERDEAAHG
210
ELRAMVLDLR
220
AFYAELYHII
230
SSNLEKIVDP
KGEEKPSMY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0008537 | proteasome activator complex |
| Molecular Function | GO:0061133 | endopeptidase activator activity |
| Biological Process | GO:2000045 | regulation of G1/S transition of mitotic cell cycle |
| Biological Process | GO:0061136 | regulation of proteasomal protein catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.