Search Results
Overview
| Uniprot ID | Q86TA1 |
|---|---|
| Protein Name | MOB kinase activator 3B |
| Gene Name | MOB3B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 20 | KTFRPKRKFEPGTQR |
Function
Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
Protein Sequence
10
MSIALKQVFN
20
KDKTFRPKRK
30
FEPGTQRFEL
40
HKRAQASLNS
50
GVDLKAAVQL
60
PSGEDQNDWV
70
AVHVVDFFNR
80
INLIYGTICE
90
FCTERTCPVM
100
SGGPKYEYRW
110
QDDLKYKKPT
120
ALPAPQYMNL
130
LMDWIEVQIN
140
NEEIFPTCVG
150
VPFPKNFLQI
160
CKKILCRLFR
170
VFVHVYIHHF
180
DRVIVMGAEA
190
HVNTCYKHFY
200
YFVTEMNLID
210
RKELEPLKEM
TSRMCH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0030295 | protein kinase activator activity |
| Biological Process | GO:0035330 | regulation of hippo signaling |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.