Search Results
Overview
| Uniprot ID | Q86VD7 |
|---|---|
| Protein Name | Mitochondrial coenzyme A transporter SLC25A42 |
| Gene Name | SLC25A42 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 66 | IIFQVSSKRFSAKEA |
Function
Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate
Protein Sequence
10
MGNGVKEGPV
20
RLHEDAEAVL
30
SSSVSSKRDH
40
RQVLSSLLSG
50
ALAGALAKTA
60
VAPLDRTKII
70
FQVSSKRFSA
80
KEAFRVLYYT
90
YLNEGFLSLW
100
RGNSATMVRV
110
VPYAAIQFSA
120
HEEYKRILGS
130
YYGFRGEALP
140
PWPRLFAGAL
150
AGTTAASLTY
160
PLDLVRARMA
170
VTPKEMYSNI
180
FHVFIRISRE
190
EGLKTLYHGF
200
MPTVLGVIPY
210
AGLSFFTYET
220
LKSLHREYSG
230
RRQPYPFERM
240
IFGACAGLIG
250
QSASYPLDVV
260
RRRMQTAGVT
270
GYPRASIART
280
LRTIVREEGA
290
VRGLYKGLSM
300
NWVKGPIAVG
310
ISFTTFDLMQ
ILLRHLQS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0043262 | ADP phosphatase activity |
| Molecular Function | GO:0015217 | ADP transmembrane transporter activity |
| Molecular Function | GO:0080122 | AMP transmembrane transporter activity |
| Molecular Function | GO:0005347 | ATP transmembrane transporter activity |
| Molecular Function | GO:0015228 | coenzyme A transmembrane transporter activity |
| Biological Process | GO:0015866 | ADP transport |
| Biological Process | GO:0080121 | AMP transport |
| Biological Process | GO:0015867 | ATP transport |
| Biological Process | GO:0035349 | coenzyme A transmembrane transport |
| Biological Process | GO:1990559 | mitochondrial coenzyme A transmembrane transport |
| Biological Process | GO:0015939 | pantothenate metabolic process |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.