Search Results
Overview
| Uniprot ID | Q86XT2 |
|---|---|
| Protein Name | Vacuolar protein sorting-associated protein 37D |
| Gene Name | VPS37D |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 167 | LRRTQAEKLQELLRR |
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation
Protein Sequence
10
MYRARAARAG
20
PEPGSPGRFG
30
ILSTGQLRDL
40
LQDEPKLDRI
50
VRLSRKFQGL
60
QLEREACLAS
70
NYALAKENLA
80
LRPRLEMGRA
90
ALAIKYQELR
100
EVAENCADKL
110
QRLEESMHRW
120
SPHCALGWLQ
130
AELEEAEQEA
140
EEQMEQLLLG
150
EQSLEAFLPA
160
FQRGRALAHL
170
RRTQAEKLQE
180
LLRRRERSAQ
190
PAPTSAADPP
200
KSFPAAAVLP
210
TGAARGPPAV
220
PRSLPPLDSR
230
PVPPLKGSPG
240
CPLGPAPLLS
250
PRPSQPEPPH
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0010008 | endosome membrane |
| Cellular Component | GO:0000813 | ESCRT I complex |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0031902 | late endosome membrane |
| Biological Process | GO:0016236 | macroautophagy |
| Biological Process | GO:0090148 | membrane fission |
| Biological Process | GO:0036258 | multivesicular body assembly |
| Biological Process | GO:0006612 | protein targeting to membrane |
| Biological Process | GO:0006623 | protein targeting to vacuole |
| Biological Process | GO:0043328 | protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| Biological Process | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| Biological Process | GO:0039702 | viral budding via host ESCRT complex |
Reference
PMID: N/A