Search Results

Overview

Uniprot ID	Q8BH86
Protein Name	D-glutamate cyclase, mitochondrial
Gene Name	Dglucy
Organism	Mus musculus

Kla Sites from experimental identification

Position	Flanking peptide
91	TICPQLQKYKFGTCT
93	CPQLQKYKFGTCTGI

Function

D-glutamate cyclase that converts D-glutamate to 5-oxo-D-proline

Protein Sequence

10 MTISFLLRSC 20 LRSAVRSLPK 30 AALIRNTSSM 40 TEGLQPASVV 50 VLPRSLAPAF 60 ESFCQGNRGP 70 LPLLGQSEAV 80 KTLPQLSAVS 90 DIRTICPQLQ 100 KYKFGTCTGI 110 LTSLEEHSEQ 120 LKEMVTFIID 130 CSFSIEEALE 140 QAGIPRRDLT 150 GPSHAGAYKT 160 TVPCATIAGF 170 CCPLVVTMRP 180 IPKDKLERLL 190 QATHAIRGQQ 200 GQPIHIGDPG 210 LLGIEALSKP 220 DYGSYVECRP 230 EDVPVFWPSP 240 LTSLEAVISC 250 KAPLAFASPP 260 GCMVMVPKDT 270 ASSASCLTPE 280 MVPEVHAISK 290 DPLHYSIVSA 300 PAAQKVRELE 310 STIAVDPGNR 320 GIGHLLLKDE 330 LLQAALSLSH 340 ARSVLVTTGF 350 PTHFNHEPPE 360 ETDGPPGAIA 370 LAAFLQALGK 380 ETAMVVDQRA 390 LNLHMRIVED 400 AIRQGVLKTP 410 IPILTYQGRS 420 MEDARAFLCK 430 DGDPKSPRFD 440 HLVAIERAGR 450 AADGNYYNAR 460 KMNIKHLVDP 470 IDDIFLAAQK 480 IPGISSTGVG 490 DGGNELGMGK 500 VKAAVKKHIR 510 NGDVIACDVE 520 ADFAVIAGVS 530 NWGGYALACA 540 LYILNSCQVH 550 ERYLRRATGP 560 SRRAGEQSWI 570 QALPSVAKEE 580 KMLGILVENQ 590 VRSGVSGIVG 600 MEVDGLPFHD 610 VHAEMIRKLV GATTVHM

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0005759	mitochondrial matrix
Cellular Component	GO:0005739	mitochondrion
Molecular Function	GO:0047820	D-glutamate cyclase activity
Biological Process	GO:0006536	glutamate metabolic process

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.