Search Results
Overview
| Uniprot ID | Q8CAK1 |
|---|---|
| Protein Name | Iron-sulfur cluster assembly factor IBA57, mitochondrial |
| Gene Name | Iba57 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 330 | LLRSETIKGPLHIKT |
Function
Mitochondrial protein involved in the maturation of mitochondrial [4Fe-4S]-proteins in the late stage of the iron-sulfur cluster assembly pathway. Operates in cooperation with ISCA2 in the maturation of [4Fe-4S] proteins
Protein Sequence
10
MAAVALLRGA
20
AVGRRSPAWH
30
WRLSGTASHC
40
LARGFGLLGS
50
NPADGVAWTC
60
FRLDGRALVR
70
VRGPDAAPFL
80
LGLSTNELPL
90
SGPPTGAAQP
100
SARAAYAHFL
110
NVQGRTLYDV
120
ILYGLPECTE
130
GAPSFLLECD
140
SSVLGALQKH
150
LSMYKIRRKV
160
TVEPSPELHV
170
WAVLPCVPQT
180
SETAPLEERV
190
EGTTMLIRDP
200
RTARMGWRLL
210
TQDDGPALVP
220
RGQLGDLQDY
230
HKYRYQQGIP
240
EGVCDLPPGM
250
ALPLESNLVF
260
MNGVSFTKGC
270
YIGQELTART
280
HHTGVIRKRL
290
FPVKLEGPLP
300
ASGVSPGAIV
310
TVTATGQAAG
320
KFRAGQGHVG
330
LALLRSETIK
340
GPLHIKTSES
350
QLVAVTAVVP
DWWPTAAK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:1990229 | iron-sulfur cluster assembly complex |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Biological Process | GO:0006783 | heme biosynthetic process |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.