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Overview

Uniprot IDQ8IUI8
Protein NameCytokine receptor-like factor 3
Gene NameCRLF3
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
90 TIEQETIKPLDDCQK

Function

May play a role in the negative regulation of cell cycle progression

Protein Sequence

10 MRGAMELEPE 20 LLLQEARENV 30 EAAQSYRREL 40 GHRLEGLREA 50 RRQIKESASQ 60 TRDVLKQHFN 70 DLKGTLGKLL 80 DERLVTLLQE 90 VDTIEQETIK 100 PLDDCQKLIE 110 HGVNTAEDLV 120 REGEIAMLGG 130 VGEENEKLWS 140 FTKKASHIQL 150 DSLPEVPLLV 160 DVPCLSAQLD 170 DSILNIVKDH 180 IFKHGTVASR 190 PPVQIEELIE 200 KPGGIIVRWC 210 KVDDDFTAQD 220 YRLQFRKCTS 230 NHFEDVYVGS 240 ETEFIVLHID 250 PNVDYQFRVC 260 ARGDGRQEWS 270 PWSVPQIGHS 280 TLVPHEWTAG 290 FEGYSLSSRR 300 NIALRNDSES 310 SGVLYSRAPT 320 YFCGQTLTFR 330 VETVGQPDRR 340 DSIGVCAEKQ 350 DGYDSLQRDQ 360 AVCISTNGAV 370 FVNGKEMTNQ 380 LPAVTSGSTV 390 TFDIEAVTLG 400 TTSNNEGGHF 410 KLRVTISSNN 420 REVVFDWLLD 430 QSCGSLYFGC 440 SFFYPGWKVL VF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0042802 identical protein binding
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Biological Process GO:0045893 positive regulation of DNA-templated transcription
Biological Process GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II

Reference

PMID: N/A