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Overview

Uniprot IDQ8IUR0
Protein NameTrafficking protein particle complex subunit 5
Gene NameTRAPPC5
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
9 EARFTRGKSALLERA

Function

May play a role in vesicular transport from endoplasmic reticulum to Golgi

Protein Sequence

10 MEARFTRGKS 20 ALLERALARP 30 RTEVSLSAFA 40 LLFSELVQHC 50 QSRVFSVAEL 60 QSRLAALGRQ 70 VGARVLDALV 80 AREKGARRET 90 KVLGALLFVK 100 GAVWKALFGK 110 EADKLEQAND 120 DARTFYIIER 130 EPLINTYISV 140 PKENSTLNCA 150 SFTAGIVEAV 160 LTHSGFPAKV 170 TAHWHKGTTL 180 MIKFEEAVIA RDRALEGR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0030008 TRAPP complex
Cellular Component GO:1990070 TRAPPI protein complex
Cellular Component GO:1990071 TRAPPII protein complex
Cellular Component GO:1990072 TRAPPIII protein complex
Biological Process GO:0048208 COPII vesicle coating
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0006901 vesicle coating
Biological Process GO:0099022 vesicle tethering

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.