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Overview

Uniprot IDQ8IVN3
Protein NameMusculoskeletal embryonic nuclear protein 1
Gene NameMUSTN1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
12 GAQEAPIKKKRPPVK
32 GARGNLTKNQEIKSK
39 KNQEIKSKTYQVMRE

Function

Required for chondrocyte development and proliferation. Plays a role in myoblast differentiation and fusion. Modulates skeletal muscle extracellular matrix composition. Plays a role in skeletal muscle function. Plays a role in glucose homeostasis

Protein Sequence

10 MSQAGAQEAP 20 IKKKRPPVKD 30 EDLKGARGNL 40 TKNQEIKSKT 50 YQVMRECEQA 60 GSAAPSVFSR 70 TRTGTETVFE 80 KPKAGPTKSV FG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Biological Process GO:0002062 chondrocyte differentiation
Biological Process GO:0035988 chondrocyte proliferation
Biological Process GO:0030326 embryonic limb morphogenesis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0007517 muscle organ development
Biological Process GO:0045663 positive regulation of myoblast differentiation
Biological Process GO:0042246 tissue regeneration

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.