Search Results
Overview
| Uniprot ID | Q8IWD4 |
|---|---|
| Protein Name | Coiled-coil domain-containing protein 117 |
| Gene Name | CCDC117 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 148 | QCEVARRKLQEIEDR |
| 196 | FDEVFTKKMIESMSR |
| 72 | VHCKKKHKREEEEDD |
Function
Facilitates DNA repair, cell cycle progression, and cell proliferation through its interaction with CIAO2B
Protein Sequence
10
MAALGRPFSG
20
LPLSGGSDFL
30
QPPQPAFPGR
40
AFPPGADGAE
50
LAPRPGPRAV
60
PSSPAGSAAR
70
GRVSVHCKKK
80
HKREEEEDDD
90
CPVRKKRITE
100
AELCAGPNDW
110
ILCAHQDVEG
120
HGVNPSVSGL
130
SIPGILDVIC
140
EEMDQTTGEP
150
QCEVARRKLQ
160
EIEDRIIDED
170
EEVEADRNVN
180
HLPSLVLSDT
190
MKTGLKREFD
200
EVFTKKMIES
210
MSRPSMELVL
220
WKPLPELLSD
230
KPKPSSNTKN
240
YTGESQAKHV
250
AAGTAFPQRT
260
ELFSEPRPTG
270
MSLYNSLETA
TSTEEEMEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:0045739 | positive regulation of DNA repair |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.