Search Results
Overview
| Uniprot ID | Q8IYI6 |
|---|---|
| Protein Name | Exocyst complex component 8 |
| Gene Name | EXOC8 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 702 | EGVGKPAKQLQDLRN |
Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane
Protein Sequence
10
MAMAMSDSGA
20
SRLRRQLESG
30
GFEARLYVKQ
40
LSQQSDGDRD
50
LQEHRQRIQA
60
LAEETAQNLK
70
RNVYQNYRQF
80
IETAREISYL
90
ESEMYQLSHL
100
LTEQKSSLES
110
IPLTLLPAAA
120
AAGAAAASGG
130
EEGVGGAGGR
140
DHLRGQAGFF
150
STPGGASRDG
160
SGPGEEGKQR
170
TLTTLLEKVE
180
GCRHLLETPG
190
QYLVYNGDLV
200
EYDADHMAQL
210
QRVHGFLMND
220
CLLVATWLPQ
230
RRGMYRYNAL
240
YSLDGLAVVN
250
VKDNPPMKDM
260
FKLLMFPESR
270
IFQAENAKIK
280
REWLEVLEDT
290
KRALSEKRRR
300
EQEEAAAPRG
310
PPQVTSKATN
320
PFEDDEEEEP
330
AVPEVEEEKV
340
DLSMEWIQEL
350
PEDLDVCIAQ
360
RDFEGAVDLL
370
DKLNHYLEDK
380
PSPPPVKELR
390
AKVEERVRQL
400
TEVLVFELSP
410
DRSLRGGPKA
420
TRRAVSQLIR
430
LGQCTKACEL
440
FLRNRAAAVH
450
TAIRQLRIEG
460
ATLLYIHKLC
470
HVFFTSLLET
480
AREFEIDFAG
490
TDSGCYSAFV
500
VWARSAMGMF
510
VDAFSKQVFD
520
SKESLSTAAE
530
CVKVAKEHCQ
540
QLGDIGLDLT
550
FIIHALLVKD
560
IQGALHSYKE
570
IIIEATKHRN
580
SEEMWRRMNL
590
MTPEALGKLK
600
EEMKSCGVSN
610
FEQYTGDDCW
620
VNLSYTVVAF
630
TKQTMGFLEE
640
ALKLYFPELH
650
MVLLESLVEI
660
ILVAVQHVDY
670
SLRCEQDPEK
680
KAFIRQNASF
690
LYETVLPVVE
700
KRFEEGVGKP
710
AKQLQDLRNA
720
SRLIRVNPES
TTSVV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0000145 | exocyst |
| Cellular Component | GO:0030426 | growth cone |
| Cellular Component | GO:0005770 | late endosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0035091 | phosphatidylinositol binding |
| Molecular Function | GO:0031267 | small GTPase binding |
| Biological Process | GO:0007032 | endosome organization |
| Biological Process | GO:0006887 | exocytosis |
| Biological Process | GO:0022617 | extracellular matrix disassembly |
| Biological Process | GO:0006893 | Golgi to plasma membrane transport |
| Biological Process | GO:0008104 | intracellular protein localization |
| Biological Process | GO:0090148 | membrane fission |
| Biological Process | GO:0000281 | mitotic cytokinesis |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0016241 | regulation of macroautophagy |
| Biological Process | GO:0006904 | vesicle docking involved in exocytosis |
| Biological Process | GO:0090522 | vesicle tethering involved in exocytosis |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.