Search Results
Overview
| Uniprot ID | Q8IZ81 |
|---|---|
| Protein Name | ELMO domain-containing protein 2 |
| Gene Name | ELMOD2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 55 | ENSLTYSKNKVLQKA |
Function
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses
Protein Sequence
10
MFISLWEFFY
20
GHFFRFWMKW
30
LLRQMTGKCE
40
LQRIFDTYVG
50
AQRTHRIENS
60
LTYSKNKVLQ
70
KATHVVQSEV
80
DKYVDDIMKE
90
KNINPEKDAS
100
FKICMKMCLL
110
QITGYKQLYL
120
DVESVRKRPY
130
DSDNLQHEEL
140
LMKLWNLLMP
150
TKKLNARISK
160
QWAEIGFQGD
170
DPKTDFRGMG
180
ILGLINLVYF
190
SENYTSEAHQ
200
ILSRSNHPKL
210
GYSYAIVGIN
220
LTEMAYSLLK
230
SEALKFHLYN
240
LVPGIPTMEH
250
FHQFYCYLVY
260
EFDKFWFEEE
270
PESIMYFNLY
280
REKFHEKIKG
290
LLLDCNVALT
LKV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Biological Process | GO:0051607 | defense response to virus |
| Biological Process | GO:0050688 | regulation of defense response to virus |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.