Search Results

Overview

Uniprot IDQ8K0Z7
Protein NameTranslational activator of cytochrome c oxidase 1
Gene NameTaco1
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
129 ALKTEKNKGIYLLYE

Function

Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1

Protein Sequence

10 MMSWAAASLR 20 MTAVPCFRVR 30 CLGFRVGPWG 40 ASQHANPGCG 50 AAPHRTLHVS 60 ATASAGHNKW 70 SKVRHIKGPK 80 DMERSRIFSK 90 LTLSIRLAVK 100 EGGPNPENNS 110 SLANILELCR 120 SKNMPKSTIE 130 SALKTEKNKG 140 IYLLYEGRGP 150 GGSSLLIEAL 160 SNSGPKCHLD 170 IKYILNKNGG 180 MMAEGARHFF 190 DKKGVVVVGV 200 EDREKKAVNL 210 ERALELAIEA 220 GAEDVKEAED 230 EEEKNLFKFI 240 CDASSLHQVR 250 KKLDSLGLCP 260 VSCSMEFIPH 270 SKVQLAEPEL 280 EQAAHLIQAL 290 NNYEDVIHVY DNIE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005739 mitochondrion
Molecular Function GO:0097177 mitochondrial ribosome binding
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0019843 rRNA binding
Biological Process GO:0033617 mitochondrial respiratory chain complex IV assembly
Biological Process GO:0061743 motor learning
Biological Process GO:0070131 positive regulation of mitochondrial translation
Biological Process GO:1904959 regulation of cytochrome-c oxidase activity
Biological Process GO:0070129 regulation of mitochondrial translation

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.