Search Results

Overview

Uniprot ID	Q8K370
Protein Name	Acyl-CoA dehydrogenase family member 10
Gene Name	Acad10
Organism	Mus musculus

Kla Sites from experimental identification

Position	Flanking peptide
1056	TVAKMELKNQSRMQE
843	KLCVFMGKTDPQAPR
948	MSRTAFGKPLVEQGT

Function

Acyl-CoA dehydrogenase only active with R- and S-2-methyl-C15-CoA

Protein Sequence

10 MLVRRLFQPS 20 TLHWAWRTTA 30 LNHPLGRHQG 40 GLRWTHSGGR 50 SYRAVIFDTG 60 GVLVPSPGTV 70 AVGWEVQNHV 80 PSGTIVKAFI 90 RGGDSGPWIR 100 FIKGEITTEH 110 FLEEFGRLCS 120 EIAKTSVPVS 130 SYFSLLTSEQ 140 VTKQFPVMTQ 150 AISQIRAKGL 160 QTAVLTNNFH 170 LSSGESFLPL 180 DRKQFDVVVE 190 SCLEGICKPD 200 PRIFQLCLQR 210 LSLQPSEAIF 220 LDDLGSNLKV 230 AASLGIHTIK 240 VDRPETAVKE 250 LEALLGFPLH 260 LGVPNTRPVR 270 KTMAIPQDAL 280 EKYLKGLLGT 290 HSTGPMELLQ 300 FDHGQSNPTY 310 YIRLADRQLV 320 LRKKPSGTLL 330 PSAHAIEREF 340 RIMKALANAG 350 VPVPTVLDLC 360 EDSSIIGTPF 370 YLMEYCPGII 380 YKDPSLPGLE 390 PSRREAIYTA 400 MNQVLCRIHS 410 VDLQATSLDS 420 FGKQGDYIPR 430 QVQTWTKQYR 440 AAETSSIPAM 450 ERLIQWLPLH 460 LPRQQRTTLV 470 HGDFRLDNLI 480 FHPEKAEVLA 490 VLDWELSTLG 500 DPFADVAYSC 510 LAYYLPSSFP 520 ILRGFRDQDV 530 TKLGIPTVEE 540 YFRMYCLNMG 550 IPPIDNWNFY 560 MAFSFFRVAA 570 ILQGVYKRSL 580 TGQASSATAQ 590 QSGKLTESMA 600 ELAWDFATKE 610 GFRVFKEMPA 620 TKTLSRSYHA 630 WAGPRSPRTP 640 KGVRGHSTVA 650 AASPSHEAKG 660 GLVISPEGLS 670 PAVRKLYEQL 680 VQFIEQKVYP 690 LEPELQRHQA 700 SADRWSPSPL 710 IEDLKEKAKA 720 EGLWNLFLPL 730 ETDPEKKYGA 740 GLTNVEYAHL 750 CEVMGMSLYA 760 SEIFNCSAPD 770 TGNMEILVRY 780 GTEEQKARWL 790 VPLLEGRIRS 800 CFAMTEPQVA 810 SSDASNIEAS 820 IKEEDGCYVI 830 NGHKWWTSGI 840 LDPRCKLCVF 850 MGKTDPQAPR 860 HQQQSMLLVP 870 MDSPGITVIR 880 PLSVFGLEDP 890 PGGHGEVRFK 900 DVRVPKENIL 910 LGPGRGFEIA 920 QGRLGPGRIH 930 HCMRLIGYSE 940 RALALMKTRV 950 MSRTAFGKPL 960 VEQGTILADI 970 ARSRVEIEQA 980 RLLVLKAAHL 990 MDVAGNKTAA 1000 LDIAMIKMVV 1010 PSMAYHVIDR 1020 AIQAFGAAGL 1030 SSDYPLAQFF 1040 GWARALRFAD 1050 GPDEVHQLTV 1060 AKMELKNQSR MQEPAVPRV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005739	mitochondrion
Molecular Function	GO:0003995	acyl-CoA dehydrogenase activity
Molecular Function	GO:0050660	flavin adenine dinucleotide binding
Biological Process	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.