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Overview

Uniprot IDQ8L5C6
Protein NameXylanase inhibitor protein 1
Gene NameXIPI
OrganismTriticum aestivum

Kla Sites from experimental identification

Position Flanking peptide
46 TVFWGRNKAEGSLRE

Function

Fungal xylanase inhibitor. Possesses competitive inhibiting activity against fungal endo-1,4-beta-D-xylanases belonging to glycoside hydrolase family 10 (GH10) and family 11 (GH11). Possesses also inhibitory activity towards barley alpha-amylases. Binding to xylanases or amylases is necessary for inhibition activity. May function in plant defense against secreted fungal pathogen xylanases. Is similar to class III chitinases, but does not exhibit chitinase activity

Protein Sequence

10 MAPLAARRPA 20 CLLALLSVAA 30 ALFLTPTALA 40 AGGKTGQVTV 50 FWGRNKAEGS 60 LREACDSGMY 70 TMVTMSFLDV 80 FGANGKYHLD 90 LSGHDLSSVG 100 ADIKHCQSKG 110 VPVSLSIGGY 120 GTGYSLPSNR 130 SALDLFDHLW 140 NSYFGGSKPS 150 VPRPFGDAWL 160 DGVDLFLEHG 170 TPADRYDVLA 180 LELAKHNIRG 190 GPGKPLHLTA 200 TVRCGYPPAA 210 HVGRALATGI 220 FERVHVRTYE 230 SDKWCNQNLG 240 WEGSWDKWTA 250 AYPATRFYVG 260 LTADDKSHQW 270 VHPKNVYYGV 280 APVAQKKDNY 290 GGIMLWDRYF 300 DKQTNYSSLI KYYA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005576 extracellular region
Molecular Function GO:0004857 enzyme inhibitor activity
Molecular Function GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0050832 defense response to fungus

Reference

[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.