Search Results

Overview

Uniprot IDQ8N0X2
Protein NameSperm-associated antigen 16 protein
Gene NameSPAG16
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
172 KNLKKDLKHYKQAAD

Function

Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity)

Protein Sequence

10 MAAQRGMPSS 20 AVRVLEEALG 30 MGLTAAGDAR 40 DTADAVAAEG 50 AYYLEQVTIT 60 EASEDDYEYE 70 EIPDDNFSIP 80 EGEEDLAKAI 90 QMAQEQATDT 100 EILERKTVLP 110 SKHAVPEVIE 120 DFLCNFLIKM 130 GMTRTLDCFQ 140 SEWYELIQKG 150 VTELRTVGNV 160 PDVYTQIMLL 170 ENENKNLKKD 180 LKHYKQAADK 190 AREDLLKIQK 200 ERDFHRMHHK 210 RIVQEKNKLI 220 NDLKGLKLHY 230 ASYEPTIRVL 240 HEKHHTLLKE 250 KMLTSLERDK 260 VVGQISGLQE 270 TLKKLQRGHS 280 YHGPQIKVDH 290 SREKENAPEG 300 PTQKGLREAR 310 EQNKCKTKMK 320 GNTKDSEFPI 330 DMQPNPNLNV 340 SKESLSPAKF 350 DYKLKNIFRL 360 HELPVSCVSM 370 QPHKDILVSC 380 GEDRLWKVLG 390 LPKCNVLLTG 400 FGHTDWLSDC 410 CFHPSGDKLA 420 TSSGDTTVKL 430 WDLCKGDCIL 440 TFEGHSRAVW 450 SCTWHSCGNF 460 VASSSLDKTS 470 KIWDVNSERC 480 RCTLYGHTDS 490 VNSIEFFPFS 500 NTLLTSSADK 510 TLSIWDARTG 520 ICEQSLYGHM 530 HSINDAIFDP 540 RGHMIASCDA 550 CGVTKLWDFR 560 KLLPIVSIDI 570 GPSPGNEVNF 580 DSSGRVLAQA 590 SGNGVIHLLD 600 LKSGEIHKLM 610 GHENEAHTVV 620 FSHDGEILFS 630 GGSDGTVRTW S

Gene Ontology

Classification GO ID Description
Cellular Component GO:1990716 axonemal central apparatus
Cellular Component GO:0005930 axoneme
Cellular Component GO:0036126 sperm flagellum
Biological Process GO:0035082 axoneme assembly
Biological Process GO:0060271 cilium assembly

Reference

[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.