Search Results
Overview
| Uniprot ID | Q8N3J6 |
|---|---|
| Protein Name | Cell adhesion molecule 2 |
| Gene Name | CADM2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 396 | GRYLARHKGTYLTNE |
Function
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes
Protein Sequence
10
MIWKRSAVLR
20
FYSVCGLLLQ
30
GSQGQFPLTQ
40
NVTVVEGGTA
50
ILTCRVDQND
60
NTSLQWSNPA
70
QQTLYFDDKK
80
ALRDNRIELV
90
RASWHELSIS
100
VSDVSLSDEG
110
QYTCSLFTMP
120
VKTSKAYLTV
130
LGVPEKPQIS
140
GFSSPVMEGD
150
LMQLTCKTSG
160
SKPAADIRWF
170
KNDKEIKDVK
180
YLKEEDANRK
190
TFTVSSTLDF
200
RVDRSDDGVA
210
VICRVDHESL
220
NATPQVAMQV
230
LEIHYTPSVK
240
IIPSTPFPQE
250
GQPLILTCES
260
KGKPLPEPVL
270
WTKDGGELPD
280
PDRMVVSGRE
290
LNILFLNKTD
300
NGTYRCEATN
310
TIGQSSAEYV
320
LIVHDVPNTL
330
LPTTIIPSLT
340
TATVTTTVAI
350
TTSPTTSATT
360
SSIRDPNALA
370
GQNGPDHALI
380
GGIVAVVVFV
390
TLCSIFLLGR
400
YLARHKGTYL
410
TNEAKGAEDA
420
PDADTAIINA
430
EGSQVNAEEK
KEYFI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0032809 | neuronal cell body membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0045202 | synapse |
| Biological Process | GO:0007156 | homophilic cell-cell adhesion |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.