Search Results
Overview
| Uniprot ID | Q8N4A0 |
|---|---|
| Protein Name | Polypeptide N-acetylgalactosaminyltransferase 4 |
| Gene Name | GALNT4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 570 | RTCDALDKNQIWSFE |
Function
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG
Protein Sequence
10
MAVRWTWAGK
20
SCLLLAFLTV
30
AYIFVELLVS
40
TFHASAGAGR
50
ARELGSRRLS
60
DLQKNTEDLS
70
RPLYKKPPAD
80
SRALGEWGKA
90
SKLQLNEDEL
100
KQQEELIERY
110
AINIYLSDRI
120
SLHRHIEDKR
130
MYECKSQKFN
140
YRTLPTTSVI
150
IAFYNEAWST
160
LLRTIHSVLE
170
TSPAVLLKEI
180
ILVDDLSDRV
190
YLKTQLETYI
200
SNLDRVRLIR
210
TNKREGLVRA
220
RLIGATFATG
230
DVLTFLDCHC
240
ECNSGWLEPL
250
LERIGRDETA
260
VVCPVIDTID
270
WNTFEFYMQI
280
GEPMIGGFDW
290
RLTFQWHSVP
300
KQERDRRISR
310
IDPIRSPTMA
320
GGLFAVSKKY
330
FQYLGTYDTG
340
MEVWGGENLE
350
LSFRVWQCGG
360
KLEIHPCSHV
370
GHVFPKRAPY
380
ARPNFLQNTA
390
RAAEVWMDEY
400
KEHFYNRNPP
410
ARKEAYGDIS
420
ERKLLRERLR
430
CKSFDWYLKN
440
VFPNLHVPED
450
RPGWHGAIRS
460
RGISSECLDY
470
NSPDNNPTGA
480
NLSLFGCHGQ
490
GGNQFFEYTS
500
NKEIRFNSVT
510
ELCAEVPEQK
520
NYVGMQNCPK
530
DGFPVPANII
540
WHFKEDGTIF
550
HPHSGLCLSA
560
YRTPEGRPDV
570
QMRTCDALDK
NQIWSFEK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0030246 | carbohydrate binding |
| Molecular Function | GO:0030145 | manganese ion binding |
| Molecular Function | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity |
| Biological Process | GO:0006493 | protein O-linked glycosylation |
| Biological Process | GO:0016266 | protein O-linked glycosylation via N-acetyl-galactosamine |
Reference
PMID: N/A