Search Results
Overview
| Uniprot ID | Q8N531 |
|---|---|
| Protein Name | F-box/LRR-repeat protein 6 |
| Gene Name | FBXL6 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 80 | RGPSAAAKPKAGLRS |
Function
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex
Protein Sequence
10
MAAPASRQVR
20
RRARAAPRPR
30
SAEDWWWDRL
40
APRGSGYHLL
50
QSDSMLLVLS
60
EPGPARPRAQ
70
RRASRRTPRQ
80
PPRGPSAAAK
90
PKAGLRSEAA
100
AAPAPAPAPT
110
PTPEEGPDAG
120
WGDRIPLEIL
130
VQIFGLLVAA
140
DGPMPFLGRA
150
ARVCRRWQEA
160
ASQPALWHTV
170
TLSSPLVGRP
180
AKGGVKAEKK
190
LLASLEWLMP
200
NRFSQLQRLT
210
LIHWKSQVHP
220
VLKLVGECCP
230
RLTFLKLSGC
240
HGVTADALVM
250
LAKACCQLHS
260
LDLQHSMVES
270
TAVVSFLEEA
280
GSRMRKLWLT
290
YSSQTTAILG
300
ALLGSCCPQL
310
QVLEVSTGIN
320
RNSIPLQLPV
330
EALQKGCPQL
340
QVLRLLNLMW
350
LPKPPGRGVA
360
PGPGFPSLEE
370
LCLASSTCNF
380
VSNEVLGRLL
390
HGSPNLRLLD
400
LRGCARITPA
410
GLQDLPCREL
420
EQLHLGLYGT
430
SDRLTLAKEG
440
SPFLTQKWCH
450
TLRELDLSGQ
460
GFSEKDLEQA
470
LAAFLSTPGG
480
SHPALCSLNL
490
RGTRVTPSTV
500
SSVISGCPGL
510
LYLNLESCRC
520
LPRGLKRAYR
530
GLEEVQWCLE
QLLTSPSPS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0019005 | SCF ubiquitin ligase complex |
| Molecular Function | GO:0004842 | ubiquitin-protein transferase activity |
| Biological Process | GO:0006508 | proteolysis |
| Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.