Search Results

Overview

Uniprot ID	Q8N608
Protein Name	Inactive dipeptidyl peptidase 10
Gene Name	DPP10
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
650	KRLSIFGKGYGGYIA

Function

Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:15454437). Has no dipeptidyl aminopeptidase activity (PubMed:12662155)

Protein Sequence

10 MNQTASVSHH 20 IKCQPSKTIK 30 ELGSNSPPQR 40 NWKGIAIALL 50 VILVVCSLIT 60 MSVILLTPDE 70 LTNSSETRLS 80 LEDLFRKDFV 90 LHDPEARWIN 100 DTDVVYKSEN 110 GHVIKLNIET 120 NATTLLLENT 130 TFVTFKASRH 140 SVSPDLKYVL 150 LAYDVKQIFH 160 YSYTASYVIY 170 NIHTREVWEL 180 NPPEVEDSVL 190 QYAAWGVQGQ 200 QLIYIFENNI 210 YYQPDIKSSS 220 LRLTSSGKEE 230 IIFNGIADWL 240 YEEELLHSHI 250 AHWWSPDGER 260 LAFLMINDSL 270 VPTMVIPRFT 280 GALYPKGKQY 290 PYPKAGQVNP 300 TIKLYVVNLY 310 GPTHTLELMP 320 PDSFKSREYY 330 ITMVKWVSNT 340 KTVVRWLNRA 350 QNISILTVCE 360 TTTGACSKKY 370 EMTSDTWLSQ 380 QNEEPVFSRD 390 GSKFFMTVPV 400 KQGGRGEFHH 410 VAMFLIQSKS 420 EQITVRHLTS 430 GNWEVIKILA 440 YDETTQKIYF 450 LSTESSPRGR 460 QLYSASTEGL 470 LNRQCISCNF 480 MKEQCTYFDA 490 SFSPMNQHFL 500 LFCEGPRVPV 510 VSLHSTDNPA 520 KYFILESNSM 530 LKEAILKKKI 540 GKPEIKILHI 550 DDYELPLQLS 560 LPKDFMDRNQ 570 YALLLIMDEE 580 PGGQLVTDKF 590 HIDWDSVLID 600 MDNVIVARFD 610 GRGSGFQGLK 620 ILQEIHRRLG 630 SVEVKDQITA 640 VKFLLKLPYI 650 DSKRLSIFGK 660 GYGGYIASMI 670 LKSDEKLFKC 680 GSVVAPITDL 690 KLYASAFSER 700 YLGMPSKEES 710 TYQAASVLHN 720 VHGLKEENIL 730 IIHGTADTKV 740 HFQHSAELIK 750 HLIKAGVNYT 760 MQVYPDEGHN 770 VSEKSKYHLY 780 STILKFFSDC 790 LKEEISVLPQ EPEEDE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0016020	membrane
Cellular Component	GO:0005886	plasma membrane
Cellular Component	GO:0008076	voltage-gated potassium channel complex
Molecular Function	GO:0015459	potassium channel regulator activity
Molecular Function	GO:0008236	serine-type peptidase activity
Molecular Function	GO:0044325	transmembrane transporter binding
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane
Biological Process	GO:0072659	protein localization to plasma membrane
Biological Process	GO:0006508	proteolysis
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.