Search Results
Overview
| Uniprot ID | Q8N6H7 |
|---|---|
| Protein Name | ADP-ribosylation factor GTPase-activating protein 2 |
| Gene Name | ARFGAP2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 216 | KSSIIGKKKPAAAKK |
Function
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes
Protein Sequence
10
MAAEPNKTEI
20
QTLFKRLRAV
30
PTNKACFDCG
40
AKNPSWASIT
50
YGVFLCIDCS
60
GVHRSLGVHL
70
SFIRSTELDS
80
NWNWFQLRCM
90
QVGGNANATA
100
FFRQHGCTAN
110
DANTKYNSRA
120
AQMYREKIRQ
130
LGSAALARHG
140
TDLWIDNMSS
150
AVPNHSPEKK
160
DSDFFTEHTQ
170
PPAWDAPATE
180
PSGTQQPAPS
190
TESSGLAQPE
200
HGPNTDLLGT
210
SPKASLELKS
220
SIIGKKKPAA
230
AKKGLGAKKG
240
LGAQKVSSQS
250
FSEIERQAQV
260
AEKLREQQAA
270
DAKKQAEESM
280
VASMRLAYQE
290
LQIDRKKEEK
300
KLQNLEGKKR
310
EQAERLGMGL
320
VSRSSVSHSV
330
LSEMQVIEQE
340
TPVSAKSSRS
350
QLDLFDDVGT
360
FASGPPKYKD
370
NPFSLGESFG
380
SRWDTDAAWG
390
MDRVEEKEPE
400
VTISSIRPIS
410
ERATNRREVE
420
SRSSGLESSE
430
ARQKFAGAKA
440
ISSDMFFGRE
450
VDAEYEARSR
460
LQQLSGSSAI
470
SSSDLFGDMD
480
GAHGAGSVSL
490
GNVLPTADIA
500
QFKQGVKSVA
510
GKMAVLANGV
520
MNSLQDRYGS
Y
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000139 | Golgi membrane |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0048205 | COPI coating of Golgi vesicle |
| Biological Process | GO:0015031 | protein transport |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.