Search Results
Overview
| Uniprot ID | Q8N6S4 |
|---|---|
| Protein Name | Ankyrin repeat domain-containing protein 13C |
| Gene Name | ANKRD13C |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 253 | SDACKIYKQGINIRL |
Function
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER
Protein Sequence
10
MTGEKIRSLR
20
RDHKPSKEEG
30
DLLEPGDEEA
40
AAALGGTFTR
50
SRIGKGGKAC
60
HKIFSNHHHR
70
LQLKAAPASS
80
NPPGAPALPL
90
HNSSVTANSQ
100
SPALLAGTNP
110
VAVVADGGSC
120
PAHYPVHECV
130
FKGDVRRLSS
140
LIRTHNIGQK
150
DNHGNTPLHL
160
AVMLGNKECA
170
HLLLAHNAPV
180
KVKNAQGWSP
190
LAEAISYGDR
200
QMITALLRKL
210
KQQSRESVEE
220
KRPRLLKALK
230
ELGDFYLELH
240
WDFQSWVPLL
250
SRILPSDACK
260
IYKQGINIRL
270
DTTLIDFTDM
280
KCQRGDLSFI
290
FNGDAAPSES
300
FVVLDNEQKV
310
YQRIHHEESE
320
METEEEVDIL
330
MSSDIYSATL
340
STKSISFTRA
350
QTGWLFREDK
360
TERVGNFLAD
370
FYLVNGLVLE
380
SRKRREHLSE
390
EDILRNKAIM
400
ESLSKGGNIM
410
EQNFEPIRRQ
420
SLTPPPQNTI
430
TWEEYISAEN
440
GKAPHLGREL
450
VCKESKKTFK
460
ATIAMSQEFP
470
LGIELLLNVL
480
EVVAPFKHFN
490
KLREFVQMKL
500
PPGFPVKLDI
510
PVFPTITATV
520
TFQEFRYDEF
530
DGSIFTIPDD
540
YKEDPSRFPD
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0140597 | protein carrier chaperone |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Biological Process | GO:0071799 | cellular response to prostaglandin D stimulus |
| Biological Process | GO:0006612 | protein targeting to membrane |
| Biological Process | GO:2000209 | regulation of anoikis |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.