Search Results

Overview

Uniprot ID	Q8N8R7
Protein Name	ARL14 effector protein
Gene Name	ARL14EP
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
177	REKRRLTKNATAGSD
84	DPFNIHKKLAKKNLH

Function

Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells

Protein Sequence

10 MMDPCSVGVQ 20 LRTTNECHKT 30 YYTRHTGFKT 40 LQELSSNDML 50 LLQLRTGMTL 60 SGNNTICFHH 70 VKIYIDRFED 80 LQKSCCDPFN 90 IHKKLAKKNL 100 HVIDLDDATF 110 LSAKFGRQLV 120 PGWKLCPKCT 130 QIINGSVDVD 140 TEDRQKRKPE 150 SDGRTAKALR 160 SLQFTNPGRQ 170 TEFAPETGKR 180 EKRRLTKNAT 190 AGSDRQVIPA 200 KSKVYDSQGL 210 LIFSGMDLCD 220 CLDEDCLGCF 230 YACPACGSTK 240 CGAECRCDRK 250 WLYEQIEIEG 260 GEIIHNKHAG

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005829	cytosol

Reference

[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.