Search Results

Overview

Uniprot IDQ8N9T8
Protein NameProtein KRI1 homolog
Gene NameKRI1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
126 ERKVILEKAGKYVDE
479 LTGKKKRKSPFAAAV
576 DKRAYSQKAQNSWKK
75 KTLSLLKKKDPRIYQ
83 KDPRIYQKDATFYNR

Function

No function data available.

Protein Sequence

10 MPEPRGSSQL 20 RVNAAFAARY 30 NRYREREELQ 40 RLKDRYGDRD 50 SSSDSSSESD 60 SSDERVEFDP 70 QQERDFYKTL 80 SLLKKKDPRI 90 YQKDATFYNR 100 TASSSDSEED 110 PEALEKQKKV 120 RPMYLKDYER 130 KVILEKAGKY 140 VDEENSDGET 150 SNHRLQETSS 160 QSYVEEQKQL 170 KESFRAFVED 180 SEDEDGAGEG 190 GSSLLQKRAK 200 TRQEKAQEEA 210 DYIEWLKGQK 220 EIRNPDSLKE 230 LTHLKEYWND 240 PELDEGERFL 250 RDYILNKRYE 260 EEEEEEEDEE 270 EMEEEEGVHG 280 PPVQLAVDDS 290 SDEGELFLKK 300 QEDFEQKYNF 310 RFEEPDSASV 320 KTYPRSIASS 330 VRRKDERRKE 340 KREETRERKK 350 REKAKKQEEL 360 KQLKNLKRKE 370 ILAKLEKLRK 380 VTGNEMLGLE 390 EGDLEDDFDP 400 AQHDQLMQKC 410 FGDEYYGAVE 420 EEKPQFEEEE 430 GLEDDWNWDT 440 WDGPEQEGDW 450 SQQELHCEDP 460 NFNMDADYDP 470 SQPRKKKREA 480 PLTGKKKRKS 490 PFAAAVGQEK 500 PVFEPGDKTF 510 EEYLDEYYRL 520 DYEDIIDDLP 530 CRFKYRTVVP 540 CDFGLSTEEI 550 LAADDKELNR 560 WCSLKKTCMY 570 RSEQEELRDK 580 RAYSQKAQNS 590 WKKRQVFKSL 600 CREEAETPAE 610 ATGKPQRDEA 620 GPQRQLPALD 630 GSLMGPESPP 640 AQEEEAPVSP 650 HKKPAPQKRR 660 RAKKARLLGP 670 TVMLGGCEFS 680 RQRLQAFGLN 690 PKRLHFRQLG 700 RQRRKQQGPK NSS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030686 90S preribosome
Cellular Component GO:0005730 nucleolus
Molecular Function GO:0003723 RNA binding
Biological Process GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Reference

[1] Bao Q, Wan N, He Z, Cao J, Yuan W et al.. Subcellular Proteomic Mapping of Lysine Lactylation.. J Am Soc Mass Spectrom 35(12):3221-3232. 2024 Dec 4. PMID: 39569522.

[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.