Search Results
Overview
| Uniprot ID | Q8N9V2 |
|---|---|
| Protein Name | Probable E3 ubiquitin-protein ligase TRIML1 |
| Gene Name | TRIML1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 165 | THEKERVKLCQEETK |
Function
Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development
Protein Sequence
10
MSTADLMENL
20
REELTCFICL
30
DYFSSPVTTE
40
CGHSFCLVCL
50
LRSWEEHNTP
60
LSCPECWRTL
70
EGPHFQSNER
80
LGRLASIARQ
90
LRSQVLQSED
100
EQGSYGRMPT
110
TAKALSDDEQ
120
GGSAFVAQSH
130
GANRVHLSSE
140
AEEHHREKLQ
150
EILNLLRVRR
160
KEAQAVLTHE
170
KERVKLCQEE
180
TKTCKQVVVS
190
EYMKMHQFLK
200
EEEQLQLQLL
210
EQEEKENMRK
220
LRNNEIKLTQ
230
QIRSLSKMIA
240
QIESSSQSSA
250
FESLEEVRGA
260
LERSEPLLLQ
270
CPEATTTELS
280
LCRITGMKEM
290
LRKFSTEITL
300
DPATANAYLV
310
LSEDLKSVKY
320
GGSRQQLPDN
330
PERFDQSATV
340
LGTQIFTSGR
350
HYWEVEVGNK
360
TEWEVGICKD
370
SVSRKGNLPK
380
PPGDLFSLIG
390
LKIGDDYSLW
400
VSSPLKGQHV
410
REPVCKVGVF
420
LDYESGHIAF
430
YNGTDESLIY
440
SFPQASFQEA
450
LRPIFSPCLP
460
NEGTNTDPLT
ICSLNSHV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0061630 | ubiquitin protein ligase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0045087 | innate immune response |
| Biological Process | GO:0016567 | protein ubiquitination |
Reference
[1] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.