Search Results
Overview
| Uniprot ID | Q8NCR6 |
|---|---|
| Protein Name | Sperm microtubule inner protein 6 |
| Gene Name | SPMIP6 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 122 | YNSSCCNKYTTYLPR |
| 30 | TSIKEVYKDPPLCAW |
Function
May participate in intramanchette transport and midpiece formation of the sperm tail. May play a potential role in somatic cell proliferation
Protein Sequence
10
MFLFSRKTRT
20
PISTYSDSYR
30
APTSIKEVYK
40
DPPLCAWEAN
50
KFLTPGLTHT
60
MERHVDPEAL
70
QKMAKCAVQD
80
YTYRGSISGH
90
PYLPEKYWLS
100
QEEADKCSPN
110
YLGSDWYNTW
120
RMEPYNSSCC
130
NKYTTYLPRL
140
PKEARMETAV
150
RGMPLECPPR
160
PERLNAYERE
170
VMVNMLNSLS
180
RNQQLPRITP
190
RCGCVDPLPG
200
RLPFHGYESA
210
CSGRHYCLRG
220
MDYYASGAPC
230
TDRRLRPWCR
240
EQPTMCTSLR
250
APARNAVCCY
260
NSPAVILPIS
EP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0002177 | manchette |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0097225 | sperm midpiece |
| Cellular Component | GO:0097228 | sperm principal piece |
| Molecular Function | GO:0043014 | alpha-tubulin binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0030317 | flagellated sperm motility |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.