Search Results

Overview

Uniprot ID	Q8NE01
Protein Name	Metal transporter CNNM3
Gene Name	CNNM3
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
519	SPLRISEKVLLHLLK

Function

Probable metal transporter

Protein Sequence

10 MAAAVAAAGR 20 LGWLFAALCL 30 GNAAGEAAPG 40 PRVLGFCLEE 50 DGAAGAGWVR 60 GGAARDTPDA 70 TFLLRLFGPG 80 FANSSWSWVA 90 PEGAGCREEA 100 ASPAGEWRAL 110 LRLRLRAEAV 120 RPHSALLAVR 130 VEPGGGAAEE 140 AAPPWALGLG 150 AAGLLALAAL 160 ARGLQLSALA 170 LAPAEVQVLR 180 ESGSEAERAA 190 ARRLEPARRW 200 AGCALGALLL 210 LASLAQAALA 220 VLLYRAAGQR 230 AVPAVLGSAG 240 LVFLVGEVVP 250 AAVSGRWTLA 260 LAPRALGLSR 270 LAVLLTLPVA 280 LPVGQLLELA 290 ARPGRLRERV 300 LELARGGGDP 310 YSDLSKGVLR 320 CRTVEDVLTP 330 LEDCFMLDAS 340 TVLDFGVLAS 350 IMQSGHTRIP 360 VYEEERSNIV 370 DMLYLKDLAF 380 VDPEDCTPLS 390 TITRFYNHPL 400 HFVFNDTKLD 410 AVLEEFKRGK 420 SHLAIVQKVN 430 NEGEGDPFYE 440 VLGLVTLEDV 450 IEEIIRSEIL 460 DESEDYRDTV 470 VKRKPASLMA 480 PLKRKEEFSL 490 FKVSDDEYKV 500 TISPQLLLAT 510 QRFLSREVDV 520 FSPLRISEKV 530 LLHLLKHPSV 540 NQEVRFDESN 550 RLATHHYLYQ 560 RSQPVDYFIL 570 ILQGRVEVEI 580 GKEGLKFENG 590 AFTYYGVSAL 600 TVPSSVHQSP 610 VSSLQPIRHD 620 LQPDPGDGTH 630 SSAYCPDYTV 640 RALSDLQLIK 650 VTRLQYLNAL 660 LATRAQNLPQ 670 SPENTDLQVI 680 PGSQTRLLGE 690 KTTTAAGSSH 700 SRPGVPVEGS PGRNPGV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0016020	membrane
Cellular Component	GO:0005886	plasma membrane
Molecular Function	GO:0022857	transmembrane transporter activity
Biological Process	GO:0010960	magnesium ion homeostasis
Biological Process	GO:0006811	monoatomic ion transport

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.