Search Results
Overview
| Uniprot ID | Q8NEF9 |
|---|---|
| Protein Name | Serum response factor-binding protein 1 |
| Gene Name | SRFBP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 178 | KETKILAKKPIHNSK |
| 190 | NSKEKIAKMEHGPKA |
| 226 | QKTPADPKLKTLSQT |
| 339 | KPSTETRKLESVFFH |
| 424 | IAVFQGKKITFDD** |
Function
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity)
Protein Sequence
10
MAQPGTLNLN
20
NEVVKMRKEV
30
KRIRVLVIRK
40
LVRSVGRLKS
50
KKGTEDALLK
60
NQRRAQRLLE
70
EIHAMKELKP
80
DIVTKSALGD
90
DINFEKIFKK
100
PDSTATERAI
110
ARLAVHPLLK
120
KKIDVLKAAV
130
QAFKEARQNV
140
AEVESSKNAS
150
EDNHSENTLY
160
SNDNGSNLQR
170
EATVISEQKV
180
KETKILAKKP
190
IHNSKEKIAK
200
MEHGPKAVTI
210
ANSPSKPSEK
220
DSVVSLESQK
230
TPADPKLKTL
240
SQTKKNKGSD
250
SSLSGNSDGG
260
EEFCEEEKEY
270
FDDSTEERFY
280
KQSSMSEDSD
290
SGDDFFIGKV
300
RRTRKKESSC
310
HSSVKEQKPL
320
EKVFLKEDTG
330
ETHGDTRNDK
340
IKPSTETRKL
350
ESVFFHSLSG
360
SKSSRRNFKE
370
QAPKTRSLDF
380
PQNEPQIKNQ
390
FNKKLSGRLE
400
NTKQQLQLPL
410
HPSWEASRRR
420
KEQQSNIAVF
QGKKITFDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030686 | 90S preribosome |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0030490 | maturation of SSU-rRNA |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.