Search Results
Overview
| Uniprot ID | Q8NEZ3 |
|---|---|
| Protein Name | WD repeat-containing protein 19 |
| Gene Name | WDR19 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 1328 | LNAAQLKKISDCTQY |
Function
As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly (PubMed:20889716, PubMed:36775821). Essential for functional IFT-A assembly and ciliary entry of GPCRs (PubMed:20889716, PubMed:36775821). Associates with the BBSome complex to mediate ciliary transport (By similarity)
Protein Sequence
10
MKRIFSLLEK
20
TWLGAPIQFA
30
WQKTSGNYLA
40
VTGADYIVKI
50
FDRHGQKRSE
60
INLPGNCVAM
70
DWDKDGDVLA
80
VIAEKSSCIY
90
LWDANTNKTS
100
QLDNGMRDQM
110
SFLLWSKVGS
120
FLAVGTVKGN
130
LLIYNHQTSR
140
KIPVLGKHTK
150
RITCGCWNAE
160
NLLALGGEDK
170
MITVSNQEGD
180
TIRQTQVRSE
190
PSNMQFFLMK
200
MDDRTSAAES
210
MISVVLGKKT
220
LFFLNLNEPD
230
NPADLEFQQD
240
FGNIVCYNWY
250
GDGRIMIGFS
260
CGHFVVISTH
270
TGELGQEIFQ
280
ARNHKDNLTS
290
IAVSQTLNKV
300
ATCGDNCIKI
310
QDLVDLKDMY
320
VILNLDEENK
330
GLGTLSWTDD
340
GQLLALSTQR
350
GSLHVFLTKL
360
PILGDACSTR
370
IAYLTSLLEV
380
TVANPVEGEL
390
PITVSVDVEP
400
NFVAVGLYHL
410
AVGMNNRAWF
420
YVLGENAVKK
430
LKDMEYLGTV
440
ASICLHSDYA
450
AALFEGKVQL
460
HLIESEILDA
470
QEERETRLFP
480
AVDDKCRILC
490
HALTSDFLIY
500
GTDTGVVQYF
510
YIEDWQFVND
520
YRHPVSVKKI
530
FPDPNGTRLV
540
FIDEKSDGFV
550
YCPVNDATYE
560
IPDFSPTIKG
570
VLWENWPMDK
580
GVFIAYDDDK
590
VYTYVFHKDT
600
IQGAKVILAG
610
STKVPFAHKP
620
LLLYNGELTC
630
QTQSGKVNNI
640
YLSTHGFLSN
650
LKDTGPDELR
660
PMLAQNLMLK
670
RFSDAWEMCR
680
ILNDEAAWNE
690
LARACLHHME
700
VEFAIRVYRR
710
IGNVGIVMSL
720
EQIKGIEDYN
730
LLAGHLAMFT
740
NDYNLAQDLY
750
LASSCPIAAL
760
EMRRDLQHWD
770
SALQLAKHLA
780
PDQIPFISKE
790
YAIQLEFAGD
800
YVNALAHYEK
810
GITGDNKEHD
820
EACLAGVAQM
830
SIRMGDIRRG
840
VNQALKHPSR
850
VLKRDCGAIL
860
ENMKQFSEAA
870
QLYEKGLYYD
880
KAASVYIRSK
890
NWAKVGDLLP
900
HVSSPKIHLQ
910
YAKAKEADGR
920
YKEAVVAYEN
930
AKQWQSVIRI
940
YLDHLNNPEK
950
AVNIVRETQS
960
LDGAKMVARF
970
FLQLGDYGSA
980
IQFLVMSKCN
990
NEAFTLAQQH
1000
NKMEIYADII
1010
GSEDTTNEDY
1020
QSIALYFEGE
1030
KRYLQAGKFF
1040
LLCGQYSRAL
1050
KHFLKCPSSE
1060
DNVAIEMAIE
1070
TVGQAKDELL
1080
TNQLIDHLLG
1090
ENDGMPKDAK
1100
YLFRLYMALK
1110
QYREAAQTAI
1120
IIAREEQSAG
1130
NYRNAHDVLF
1140
SMYAELKSQK
1150
IKIPSEMATN
1160
LMILHSYILV
1170
KIHVKNGDHM
1180
KGARMLIRVA
1190
NNISKFPSHI
1200
VPILTSTVIE
1210
CHRAGLKNSA
1220
FSFAAMLMRP
1230
EYRSKIDAKY
1240
KKKIEGMVRR
1250
PDISEIEEAT
1260
TPCPFCKFLL
1270
PECELLCPGC
1280
KNSIPYCIAT
1290
GRHMLKDDWT
1300
VCPHCDFPAL
1310
YSELKIMLNT
1320
ESTCPMCSER
1330
LNAAQLKKIS
1340
DCTQYLRTEE
EL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0032391 | photoreceptor connecting cilium |
| Cellular Component | GO:0001750 | photoreceptor outer segment |
| Cellular Component | GO:0097225 | sperm midpiece |
| Cellular Component | GO:0097228 | sperm principal piece |
| Biological Process | GO:0060271 | cilium assembly |
| Biological Process | GO:0035721 | intraciliary retrograde transport |
| Biological Process | GO:1903441 | protein localization to ciliary membrane |
| Biological Process | GO:0097499 | protein localization to non-motile cilium |
| Biological Process | GO:0065003 | protein-containing complex assembly |
| Cellular Component | GO:0097542 | ciliary tip |
| Cellular Component | GO:0005929 | cilium |
| Cellular Component | GO:0030991 | intraciliary transport particle A |
| Cellular Component | GO:0031514 | motile cilium |
| Cellular Component | GO:0097730 | non-motile cilium |
Reference
PMID: N/A