Search Results
Overview
| Uniprot ID | Q8NFZ8 |
|---|---|
| Protein Name | Cell adhesion molecule 4 |
| Gene Name | CADM4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 191 | VRFRVDRKDDGGIII |
Function
Cell adhesion molecule, exhibiting calcium- and magnesium-independent cell-cell adhesion activity (PubMed:16261159). In its palmitoylated form, is required for proper oligodendrocyte maturation and myelination in CNS via its association with other cell adhesion molecules such as CADM2/3 and MAG (By similarity). May have tumor-suppressor activity (PubMed:16261159)
Protein Sequence
10
MGRARRFQWP
20
LLLLWAAAAG
30
PGAGQEVQTE
40
NVTVAEGGVA
50
EITCRLHQYD
60
GSIVVIQNPA
70
RQTLFFNGTR
80
ALKDERFQLE
90
EFSPRRVRIR
100
LSDARLEDEG
110
GYFCQLYTED
120
THHQIATLTV
130
LVAPENPVVE
140
VREQAVEGGE
150
VELSCLVPRS
160
RPAATLRWYR
170
DRKELKGVSS
180
SQENGKVWSV
190
ASTVRFRVDR
200
KDDGGIIICE
210
AQNQALPSGH
220
SKQTQYVLDV
230
QYSPTARIHA
240
SQAVVREGDT
250
LVLTCAVTGN
260
PRPNQIRWNR
270
GNESLPERAE
280
AVGETLTLPG
290
LVSADNGTYT
300
CEASNKHGHA
310
RALYVLVVYD
320
PGAVVEAQTS
330
VPYAIVGGIL
340
ALLVFLIICV
350
LVGMVWCSVR
360
QKGSYLTHEA
370
SGLDEQGEAR
380
EAFLNGSDGH
KRKEEFFI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031252 | cell leading edge |
| Cellular Component | GO:0044291 | cell-cell contact zone |
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0019903 | protein phosphatase binding |
| Molecular Function | GO:0030971 | receptor tyrosine kinase binding |
| Molecular Function | GO:0043183 | vascular endothelial growth factor receptor 1 binding |
| Molecular Function | GO:0043184 | vascular endothelial growth factor receptor 2 binding |
| Biological Process | GO:0007156 | homophilic cell-cell adhesion |
| Biological Process | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation |
| Biological Process | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation |
| Biological Process | GO:0001933 | negative regulation of protein phosphorylation |
| Biological Process | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway |
| Biological Process | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway |
| Biological Process | GO:2000145 | regulation of cell motility |
| Biological Process | GO:0042127 | regulation of cell population proliferation |
| Biological Process | GO:0001932 | regulation of protein phosphorylation |
| Biological Process | GO:0035020 | regulation of Rac protein signal transduction |
| Biological Process | GO:0061041 | regulation of wound healing |
Reference
PMID: N/A