Search Results

Overview

Uniprot ID	Q8NG27
Protein Name	E3 ubiquitin-protein ligase Praja-1
Gene Name	PJA1
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
337	SDQVKPEKVPRRRRT

Function

Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting

Protein Sequence

10 MGQESSKPVW 20 PNPTGGYQSN 30 TGRRYGRRHA 40 YVSFRPPTSQ 50 RERIASQRKT 60 NSEVPMHRSA 70 PSQTTKRSRS 80 PFSTTRRSWD 90 DSESSGTNLN 100 IDNEDYSRYP 110 PREYRASGSR 120 RGMAYGHIDS 130 YGADDSEEEG 140 AGPVERPPVR 150 GKTGKFKDDK 160 LYDPEKGARS 170 LAGPPPHFSS 180 FSRDVREERD 190 KLDPVPAARC 200 SASRADFLPQ 210 SSVASQSSSE 220 GKLATKGDSS 230 ERERREQNLP 240 ARPSRAPVSI 250 CGGGENTSKS 260 AEEPVVRPKI 270 RNLASPNCVK 280 PKIFFDTDDD 290 DDMPHSTSRW 300 RDTANDNEGH 310 SDGLARRGRG 320 ESSSGYPEPK 330 YPEDKREARS 340 DQVKPEKVPR 350 RRRTMADPDF 360 WTHSDDYYKY 370 CDEDSDSDKE 380 WIAALRRKYR 390 SREQTLSSSG 400 ESWETLPGKE 410 EREPPQAKVS 420 ASTGTSPGPG 430 ASASAGAGAG 440 ASAGSNGSNY 450 LEEVREPSLQ 460 EEQASLEEGE 470 IPWLQYHEND 480 SSSEGDNDSG 490 HELMQPGVFM 500 LDGNNNLEDD 510 SSVSEDLEVD 520 WSLFDGFADG 530 LGVAEAISYV 540 DPQFLTYMAL 550 EERLAQAMET 560 ALAHLESLAV 570 DVEVANPPAS 580 KESIDALPEI 590 LVTEDHGAVG 600 QEMCCPICCS 610 EYVKGEVATE 620 LPCHHYFHKP 630 CVSIWLQKSG 640 TCPVCRCMFP PPL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Molecular Function	GO:0061630	ubiquitin protein ligase activity
Molecular Function	GO:0008270	zinc ion binding
Biological Process	GO:0016567	protein ubiquitination

Reference

PMID: N/A