Search Results
Overview
| Uniprot ID | Q8NHQ1 |
|---|---|
| Protein Name | Centrosomal protein of 70 kDa |
| Gene Name | CEP70 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 149 | NKIKDLQKEQKTLQV |
| 152 | KDLQKEQKTLQVKCQ |
| 330 | KKAEDTEKKDEPSKY |
Function
Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle
Protein Sequence
10
MFPVAPKPQD
20
SSQPSDRLMT
30
EKQQEEAEWE
40
SINVLLMMHG
50
LKPLSLVKRT
60
DLKDLIIFDK
70
QSSQRMRQNL
80
KLLVEETSCQ
90
QNMIQELIET
100
NQQLRNELQL
110
EQSRAANQEQ
120
RANDLEQIME
130
SVKSKIGELE
140
DESLSRACHQ
150
QNKIKDLQKE
160
QKTLQVKCQH
170
YKKKRTEQEE
180
TIASLQMEVC
190
RLKKEEEDRI
200
VTQNRVFAYL
210
CKRVPHTVLD
220
RQLLCLIDYY
230
ESKIRKIHTQ
240
RQYKEDESQS
250
EEENDYRNLD
260
ASPTYKGLLM
270
SLQNQLKESK
280
SKIDALSSEK
290
LNLQKDLETR
300
PTQHELRLYK
310
QQVKKLEKAL
320
KKNVKLQELI
330
NHKKAEDTEK
340
KDEPSKYNQQ
350
QALIDQRYFQ
360
VLCSINSIIH
370
NPRAPVIIYK
380
QTKGGVQNFN
390
KDLVQDCGFE
400
HLVPVIEMWA
410
DQLTSLKDLY
420
KSLKTLSAEL
430
VPWLNLKKQD
440
ENEGIKVEDL
450
LFIVDTMLEE
460
VENKEKDSNM
470
PHFQTLQAIV
480
SHFQKLFDVP
490
SLNGVYPRMN
500
EVYTRLGEMN
510
NAVRNLQELL
520
ELDSSSSLCV
530
LVSTVGKLCR
540
LINEDVNEQV
550
MQVLGPEDLQ
560
SIIYKLEEHE
570
EFFPAFQAFT
580
NDLLEILEID
590
DLDAIVPAVK
KLKVLSY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005815 | microtubule organizing center |
| Molecular Function | GO:0043015 | gamma-tubulin binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:0060271 | cilium assembly |
| Biological Process | GO:0070507 | regulation of microtubule cytoskeleton organization |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.