Search Results
Overview
| Uniprot ID | Q8TB36 |
|---|---|
| Protein Name | Ganglioside-induced differentiation-associated protein 1 |
| Gene Name | GDAP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 188 | LQEAYIAKQKRLKSK |
| 195 | KQKRLKSKLLDHDNV |
| 203 | LLDHDNVKYLKKILD |
| 207 | DNVKYLKKILDELEK |
| 47 | VRLVIAEKALKCEEH |
Function
Regulates the mitochondrial network by promoting mitochondrial fission
Protein Sequence
10
MAERQEEQRG
20
SPPLRAEGKA
30
DAEVKLILYH
40
WTHSFSSQKV
50
RLVIAEKALK
60
CEEHDVSLPL
70
SEHNEPWFMR
80
LNSTGEVPVL
90
IHGENIICEA
100
TQIIDYLEQT
110
FLDERTPRLM
120
PDKESMYYPR
130
VQHYRELLDS
140
LPMDAYTHGC
150
ILHPELTVDS
160
MIPAYATTRI
170
RSQIGNTESE
180
LKKLAEENPD
190
LQEAYIAKQK
200
RLKSKLLDHD
210
NVKYLKKILD
220
ELEKVLDQVE
230
TELQRRNEET
240
PEEGQQPWLC
250
GESFTLADVS
260
LAVTLHRLKF
270
LGFARRNWGN
280
GKRPNLETYY
290
ERVLKRKTFN
300
KVLGHVNNIL
310
ISAVLPTAFR
320
VAKKRAPKVL
330
GTTLVVGLLA
340
GVGYFAFMLF
350
RKRLGSMILA
FRPRPNYF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005778 | peroxisomal membrane |
| Biological Process | GO:0071305 | cellular response to vitamin D |
| Biological Process | GO:0000266 | mitochondrial fission |
| Biological Process | GO:0008053 | mitochondrial fusion |
| Biological Process | GO:0006626 | protein targeting to mitochondrion |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.