Search Results
Overview
| Uniprot ID | Q8TBF4 |
|---|---|
| Protein Name | Zinc finger CCHC-type and RNA-binding motif-containing protein 1 |
| Gene Name | ZCRB1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 104 | RRRNYFDKSKCYECG |
| 186 | EEEQKKWKPSSGVPS |
| 43 | VVKVTIMKDKDTRKS |
| 45 | KVTIMKDKDTRKSKG |
Function
No function data available.
Protein Sequence
10
MSGGLAPSKS
20
TVYVSNLPFS
30
LTNNDLYRIF
40
SKYGKVVKVT
50
IMKDKDTRKS
60
KGVAFILFLD
70
KDSAQNCTRA
80
INNKQLFGRV
90
IKASIAIDNG
100
RAAEFIRRRN
110
YFDKSKCYEC
120
GESGHLSYAC
130
PKNMLGEREP
140
PKKKEKKKKK
150
KAPEPEEEIE
160
EVEESEDEGE
170
DPALDSLSQA
180
IAFQQAKIEE
190
EQKKWKPSSG
200
VPSTSDDSRR
210
PRIKKSTYFS
DEEELSD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005689 | U12-type spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.
[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[3] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.