Search Results
Overview
| Uniprot ID | Q8TBG4 |
|---|---|
| Protein Name | Ethanolamine-phosphate phospho-lyase |
| Gene Name | ETNPPL |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 455 | TSENTPCKTKMLKEA |
Function
Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde
Protein Sequence
10
MCELYSKRDT
20
LGLRKKHIGP
30
SCKVFFASDP
40
IKIVRAQRQY
50
MFDENGEQYL
60
DCINNVAHVG
70
HCHPGVVKAA
80
LKQMELLNTN
90
SRFLHDNIVE
100
YAKRLSATLP
110
EKLSVCYFTN
120
SGSEANDLAL
130
RLARQFRGHQ
140
DVITLDHAYH
150
GHLSSLIEIS
160
PYKFQKGKDV
170
KKEFVHVAPT
180
PDTYRGKYRE
190
DHADSASAYA
200
DEVKKIIEDA
210
HNSGRKIAAF
220
IAESMQSCGG
230
QIIPPAGYFQ
240
KVAEYVHGAG
250
GVFIADEVQV
260
GFGRVGKHFW
270
SFQMYGEDFV
280
PDIVTMGKPM
290
GNGHPVACVV
300
TTKEIAEAFS
310
SSGMEYFNTY
320
GGNPVSCAVG
330
LAVLDIIENE
340
DLQGNAKRVG
350
NYLTELLKKQ
360
KAKHTLIGDI
370
RGIGLFIGID
380
LVKDHLKRTP
390
ATAEAQHIIY
400
KMKEKRVLLS
410
ADGPHRNVLK
420
IKPPMCFTEE
430
DAKFMVDQLD
440
RILTVLEEAM
450
GTKTESVTSE
460
NTPCKTKMLK
470
EAHIELLRDS
480
TTDSKENPSR
490
KRNGMCTDTH
SLLSKRLKT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Molecular Function | GO:0050459 | ethanolamine-phosphate phospho-lyase activity |
| Molecular Function | GO:0030170 | pyridoxal phosphate binding |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.