Search Results
Overview
| Uniprot ID | Q8TDU9 |
|---|---|
| Protein Name | Relaxin-3 receptor 2 |
| Gene Name | RXFP4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 345 | WVQQVALKQVGRRWV |
Function
High affinity receptor for INSL5. Also acts as a receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation
Protein Sequence
10
MPTLNTSASP
20
PTFFWANASG
30
GSVLSADDAP
40
MPVKFLALRL
50
MVALAYGLVG
60
AIGLLGNLAV
70
LWVLSNCARR
80
APGPPSDTFV
90
FNLALADLGL
100
ALTLPFWAAE
110
SALDFHWPFG
120
GALCKMVLTA
130
TVLNVYASIF
140
LITALSVARY
150
WVVAMAAGPG
160
THLSLFWARI
170
ATLAVWAAAA
180
LVTVPTAVFG
190
VEGEVCGVRL
200
CLLRFPSRYW
210
LGAYQLQRVV
220
LAFMVPLGVI
230
TTSYLLLLAF
240
LQRRQRRRQD
250
SRVVARSVRI
260
LVASFFLCWF
270
PNHVVTLWGV
280
LVKFDLVPWN
290
STFYTIQTYV
300
FPVTTCLAHS
310
NSCLNPVLYC
320
LLRREPRQAL
330
AGTFRDLRLR
340
LWPQGGGWVQ
350
QVALKQVGRR
360
WVASNPRESR
370
PSTLLTNLDR
GTPG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0004966 | galanin receptor activity |
| Biological Process | GO:0007218 | neuropeptide signaling pathway |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.