Search Results
Overview
| Uniprot ID | Q8TE67 |
|---|---|
| Protein Name | Epidermal growth factor receptor kinase substrate 8-like protein 3 |
| Gene Name | EPS8L3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | RAIYLHRKEYSQNLT |
| 274 | KKFGKKNKDQGGLTQ |
| 484 | LEVLDHSKRWWLVKN |
Function
No function data available.
Protein Sequence
10
MSRPSSRAIY
20
LHRKEYSQNL
30
TSEPTLLQHR
40
VEHLMTCKQG
50
SQRVQGPEDA
60
LQKLFEMDAQ
70
GRVWSQDLIL
80
QVRDGWLQLL
90
DIETKEELDS
100
YRLDSIQAMN
110
VALNTCSYNS
120
ILSITVQEPG
130
LPGTSTLLFQ
140
CQEVGAERLK
150
TSLQKALEEE
160
LEQRPRLGGL
170
QPGQDRWRGP
180
AMERPLPMEQ
190
ARYLEPGIPP
200
EQPHQRTLEH
210
SLPPSPRPLP
220
RHTSAREPSA
230
FTLPPPRRSS
240
SPEDPERDEE
250
VLNHVLRDIE
260
LFMGKLEKAQ
270
AKTSRKKKFG
280
KKNKDQGGLT
290
QAQYIDCFQK
300
IKHSFNLLGR
310
LATWLKETSA
320
PELVHILFKS
330
LNFILARCPE
340
AGLAAQVISP
350
LLTPKAINLL
360
QSCLSPPESN
370
LWMGLGPAWT
380
TSRADWTGDE
390
PLPYQPTFSD
400
DWQLPEPSSQ
410
APLGYQDPVS
420
LRRGSHRLGS
430
TSHFPQEKTH
440
NHDPQPGDPN
450
SRPSSPKPAQ
460
PALKMQVLYE
470
FEARNPRELT
480
VVQGEKLEVL
490
DHSKRWWLVK
500
NEAGRSGYIP
510
SNILEPLQPG
520
TPGTQGQSPS
530
RVPMLRLSSR
540
PEEVTDWLQA
550
ENFSTATVRT
560
LGSLTGSQLL
570
RIRPGELQML
580
CPQEAPRILS
590
RLEAVRRMLG
ISP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0032587 | ruffle membrane |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0005085 | guanyl-nucleotide exchange factor activity |
| Biological Process | GO:1900029 | positive regulation of ruffle assembly |
| Biological Process | GO:0042634 | regulation of hair cycle |
| Biological Process | GO:0035023 | regulation of Rho protein signal transduction |
| Biological Process | GO:0007266 | Rho protein signal transduction |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.