Search Results

Overview

Uniprot IDQ8WUU5
Protein NameGATA zinc finger domain-containing protein 1
Gene NameGATAD1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
101 RLRNTKYKSAPAAEK

Function

Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3)

Protein Sequence

10 MPLGLKPTCS 20 VCKTTSSSMW 30 KKGAQGEILC 40 HHCTGRGGAG 50 SGGAGSGAAG 60 GTGGSGGGGF 70 GAATFASTSA 80 TPPQSNGGGG 90 GKQSKQEIHR 100 RSARLRNTKY 110 KSAPAAEKKV 120 STKGKGRRHI 130 FKLKNPIKAP 140 ESVSTIITAE 150 SIFYKGVYYQ 160 IGDVVSVIDE 170 QDGKPYYAQI 180 RGFIQDQYCE 190 KSAALTWLIP 200 TLSSPRDQFD 210 PASYIIGPEE 220 DLPRKMEYLE 230 FVCHAPSEYF 240 KSRSSPFPTV 250 PTRPEKGYIW 260 THVGPTPAIT IKESVANHL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0043565 sequence-specific DNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006325 chromatin organization
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0006355 regulation of DNA-templated transcription

Reference

[1] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.