Search Results
Overview
| Uniprot ID | Q8WVM8 |
|---|---|
| Protein Name | Sec1 family domain-containing protein 1 |
| Gene Name | SCFD1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 541 | GVKNLVLKQQNLPVT |
| 572 | DYRYFDPKMLRGNDS |
Function
Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity)
Protein Sequence
10
MAAAAAATAA
20
AAASIRERQT
30
VALKRMLNFN
40
VPHIKNSTGE
50
PVWKVLIYDR
60
FGQDIISPLL
70
SVKELRDMGI
80
TLHLLLHSDR
90
DPIPDVPAVY
100
FVMPTEENID
110
RMCQDLRNQL
120
YESYYLNFIS
130
AISRSKLEDI
140
ANAALAASAV
150
TQVAKVFDQY
160
LNFITLEDDM
170
FVLCNQNKEL
180
VSYRAINRPD
190
ITDTEMETVM
200
DTIVDSLFCF
210
FVTLGAVPII
220
RCSRGTAAEM
230
VAVKLDKKLR
240
ENLRDARNSL
250
FTGDTLGAGQ
260
FSFQRPLLVL
270
VDRNIDLATP
280
LHHTWTYQAL
290
VHDVLDFHLN
300
RVNLEESSGV
310
ENSPAGARPK
320
RKNKKSYDLT
330
PVDKFWQKHK
340
GSPFPEVAES
350
VQQELESYRA
360
QEDEVKRLKS
370
IMGLEGEDEG
380
AISMLSDNTA
390
KLTSAVSSLP
400
ELLEKKRLID
410
LHTNVATAVL
420
EHIKARKLDV
430
YFEYEEKIMS
440
KTTLDKSLLD
450
IISDPDAGTP
460
EDKMRLFLIY
470
YISTQQAPSE
480
ADLEQYKKAL
490
TDAGCNLNPL
500
QYIKQWKAFT
510
KMASAPASYG
520
STTTKPMGLL
530
SRVMNTGSQF
540
VMEGVKNLVL
550
KQQNLPVTRI
560
LDNLMEMKSN
570
PETDDYRYFD
580
PKMLRGNDSS
590
VPRNKNPFQE
600
AIVFVVGGGN
610
YIEYQNLVDY
620
IKGKQGKHIL
630
YGCSELFNAT
640
QFIKQLSQLG
QK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0006892 | post-Golgi vesicle-mediated transport |
| Cellular Component | GO:0005801 | cis-Golgi network |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0032580 | Golgi cisterna membrane |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0005798 | Golgi-associated vesicle |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0019905 | syntaxin binding |
| Biological Process | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:1902902 | negative regulation of autophagosome assembly |
| Biological Process | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport |
| Biological Process | GO:0051223 | regulation of protein transport |
| Biological Process | GO:0009636 | response to toxic substance |
| Biological Process | GO:0006890 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.