Search Results

Overview

Uniprot ID	Q8WWI1
Protein Name	LIM domain only protein 7
Gene Name	LMO7
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
1191	ASESISLKNLKRRSQ
1456	SSQRRSKKEQVPSGA
782	KRSSKTFKEMLQDRE

Function

No function data available.

Protein Sequence

10 MKKIRICHIF 20 TFYSWMSYDV 30 LFQRTELGAL 40 EIWRQLICAH 50 VCICVGWLYL 60 RDRVCSKKDI 70 ILRTEQNSGR 80 TILIKAVTEK 90 NFETKDFRAS 100 LENGVLLCDL 110 INKLKPGVIK 120 KINRLSTPIA 130 GLDNINVFLK 140 ACEQIGLKEA 150 QLFHPGDLQD 160 LSNRVTVKQE 170 ETDRRVKNVL 180 ITLYWLGRKA 190 QSNPYYNGPH 200 LNLKAFENLL 210 GQALTKALED 220 SSFLKRSGRD 230 SGYGDIWCPE 240 RGEFLAPPRH 250 HKREDSFESL 260 DSLGSRSLTS 270 CSSDITLRGG 280 REGFESDTDS 290 EFTFKMQDYN 300 KDDMSYRRIS 310 AVEPKTALPF 320 NRFLPNKSRQ 330 PSYVPAPLRK 340 KKPDKHEDNR 350 RSWASPVYTE 360 ADGTFSSNQR 370 RIWGTNVENW 380 PTVQGTSKSS 390 CYLEEEKAKT 400 RSIPNIVKDD 410 LYVRKLSPVM 420 PNPGNAFDQF 430 LPKCWTPEDV 440 NWKRIKRETY 450 KPWYKEFQGF 460 SQFLLLQALQ 470 TYSDDILSSE 480 THTKIDPTSG 490 PRLITRRKNL 500 SYAPGYRRDD 510 LEMAALDPDL 520 ENDDFFVRKT 530 GVFHANPYVL 540 RAFEDFRKFS 550 EQDDSVERDI 560 ILQCREGELV 570 LPDLEKDDMI 580 VRRIPAQKKE 590 VPLSGAPDRY 600 HPVPFPEPWT 610 LPPEIQAKFL 620 CVFERTCPSK 630 EKSNSCRILV 640 PSYRQKKDDM 650 LTRKIQSWKL 660 GTTVPPISFT 670 PGPCSEADLK 680 RWEAIREASR 690 LRHKKRLMVE 700 RLFQKIYGEN 710 GSKSMSDVSA 720 EDVQNLRQLR 730 YEEMQKIKSQ 740 LKEQDQKWQD 750 DLAKWKDRRK 760 SYTSDLQKKK 770 EEREEIEKQA 780 LEKSKRSSKT 790 FKEMLQDRES 800 QNQKSTVPSR 810 RRMYSFDDVL 820 EEGKRPPTMT 830 VSEASYQSER 840 VEEKGATYPS 850 EIPKEDSTTF 860 AKREDRVTTE 870 IQLPSQSPVE 880 EQSPASLSSL 890 RSRSTQMEST 900 RVSASLPRSY 910 RKTDTVRLTS 920 VVTPRPFGSQ 930 TRGISSLPRS 940 YTMDDAWKYN 950 GDVEDIKRTP 960 NNVVSTPAPS 970 PDASQLASSL 980 SSQKEVAATE 990 EDVTRLPSPT 1000 SPFSSLSQDQ 1010 AATSKATLSS 1020 TSGLDLMSES 1030 GEGEISPQRE 1040 VSRSQDQFSD 1050 MRISINQTPG 1060 KSLDFGFTIK 1070 WDIPGIFVAS 1080 VEAGSPAEFS 1090 QLQVDDEIIA 1100 INNTKFSYND 1110 SKEWEEAMAK 1120 AQETGHLVMD 1130 VRRYGKAGSP 1140 ETKWIDATSG 1150 IYNSEKSSNL 1160 SVTTDFSESL 1170 QSSNIESKEI 1180 NGIHDESNAF 1190 ESKASESISL 1200 KNLKRRSQFF 1210 EQGSSDSVVP 1220 DLPVPTISAP 1230 SRWVWDQEEE 1240 RKRQERWQKE 1250 QDRLLQEKYQ 1260 REQEKLREEW 1270 QRAKQEAERE 1280 NSKYLDEELM 1290 VLSSNSMSLT 1300 TREPSLATWE 1310 ATWSEGSKSS 1320 DREGTRAGEE 1330 ERRQPQEEVV 1340 HEDQGKKPQD 1350 QLVIERERKW 1360 EQQLQEEQEQ 1370 KRLQAEAEEQ 1380 KRPAEEQKRQ 1390 AEIERETSVR 1400 IYQYRRPVDS 1410 YDIPKTEEAS 1420 SGFLPGDRNK 1430 SRSTTELDDY 1440 STNKNGNNKY 1450 LDQIGNMTSS 1460 QRRSKKEQVP 1470 SGAELERQQI 1480 LQEMRKRTPL 1490 HNDNSWIRQR 1500 SASVNKEPVS 1510 LPGIMRRGES 1520 LDNLDSPRSN 1530 SWRQPPWLNQ 1540 PTGFYASSSV 1550 QDFSRPPPQL 1560 VSTSNRAYMR 1570 NPSSSVPPPS 1580 AGSVKTSTTG 1590 VATTQSPTPR 1600 SHSPSASQSG 1610 SQLRNRSVSG 1620 KRICSYCNNI 1630 LGKGAAMIIE 1640 SLGLCYHLHC 1650 FKCVACECDL 1660 GGSSSGAEVR 1670 IRNHQLYCND 1680 CYLRFKSGRP TAM

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0015629	actin cytoskeleton
Cellular Component	GO:0016324	apical plasma membrane
Cellular Component	GO:0009986	cell surface
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0005925	focal adhesion
Cellular Component	GO:0005739	mitochondrion
Cellular Component	GO:0005635	nuclear envelope
Cellular Component	GO:0005634	nucleus
Cellular Component	GO:0000151	ubiquitin ligase complex
Molecular Function	GO:0046872	metal ion binding
Molecular Function	GO:0004842	ubiquitin-protein transferase activity
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0016567	protein ubiquitination
Biological Process	GO:0030155	regulation of cell adhesion
Biological Process	GO:0023051	regulation of signaling
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[3] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.