Search Results
Overview
| Uniprot ID | Q8WXF0 |
|---|---|
| Protein Name | Serine/arginine-rich splicing factor 12 |
| Gene Name | SRSF12 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 237 | GYTNSETKVQTAKHS |
Function
Splicing factor that seems to antagonize SR proteins in pre-mRNA splicing regulation
Protein Sequence
10
MSRYTRPPNT
20
SLFIRNVADA
30
TRPEDLRREF
40
GRYGPIVDVY
50
IPLDFYTRRP
60
RGFAYVQFED
70
VRDAEDALYN
80
LNRKWVCGRQ
90
IEIQFAQGDR
100
KTPGQMKSKE
110
RHPCSPSDHR
120
RSRSPSQRRT
130
RSRSSSWGRN
140
RRRSDSLKES
150
RHRRFSYSQS
160
KSRSKSLPRR
170
STSARQSRTP
180
RRNFGSRGRS
190
RSKSLQKRSK
200
SIGKSQSSSP
210
QKQTSSGTKS
220
RSHGRHSDSI
230
ARSPCKSPKG
240
YTNSETKVQT
250
AKHSHFRSHS
260
RSRSYRHKNS
W
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0050733 | RS domain binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0000395 | mRNA 5'-splice site recognition |
| Biological Process | GO:0048025 | negative regulation of mRNA splicing, via spliceosome |
| Biological Process | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0000244 | spliceosomal tri-snRNP complex assembly |
Reference
PMID: N/A